Gene Symbol | KRTAP12-3 |
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Entrez Gene | 386683 |
Alt Symbol | KRTAP12.3 |
Species | Human |
Gene Type | protein-coding |
Description | keratin associated protein 12-3 |
Other Description | high sulfur keratin-associated protein 12.3|keratin-associated protein 12-3|keratin-associated protein 12.3 |
Swissprots | P60328 |
Accessions | EAX09407 P60328 AB076361 BAD01548 BC160116 AAI60116 NM_198697 NP_941970 |
Function | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins. |
Tissue Specificity | Restricted to a narrow region of the hair fiber cuticle, lying approximately 20 cell layers above the apex of the dermal papilla of the hair root; not detected in any other tissues. {ECO:0000269|PubMed:14962103, ECO:0000269|PubMed:15028290}. |
Recombinant Human KRTAP12-3 - KRTAP12-3-1552H from Creative Biomart
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Recombinant Human Keratin-associated protein 12-3(KRTAP12-3) - CSB-YP012607HU CSB-EP012607HU CSB-BP012607HU CSB-MP012607HU from Cusabio
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KRTAP12-3 Peptide, Human - M34GP08426H from Creative Peptides
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Keratin-associated protein 12-3 (KRTAP12-3), Recombinant Protein - MBS951621 from MyBioSource
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