Gene Symbol | KRTAP12-3 |
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Entrez Gene | 386683 |
Alt Symbol | KRTAP12.3 |
Species | Human |
Gene Type | protein-coding |
Description | keratin associated protein 12-3 |
Other Description | high sulfur keratin-associated protein 12.3|keratin-associated protein 12-3|keratin-associated protein 12.3 |
Swissprots | P60328 |
Accessions | EAX09407 P60328 AB076361 BAD01548 BC160116 AAI60116 NM_198697 NP_941970 |
Function | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins. |
Tissue Specificity | Restricted to a narrow region of the hair fiber cuticle, lying approximately 20 cell layers above the apex of the dermal papilla of the hair root; not detected in any other tissues. {ECO:0000269|PubMed:14962103, ECO:0000269|PubMed:15028290}. |
KRTAP12-3 CRISPR/Cas9 KO Plasmid (h) - sc-415733 from Santa Cruz Biotechnology
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KRTAP12-3 HDR Plasmid (h) - sc-415733-HDR from Santa Cruz Biotechnology
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KRTAP12-3 Double Nickase Plasmid (h) - sc-415733-NIC from Santa Cruz Biotechnology
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KRTAP12-3 Double Nickase Plasmid (h2) - sc-415733-NIC-2 from Santa Cruz Biotechnology
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KRTAP12-3 CRISPR Activation Plasmid (h) - sc-415733-ACT from Santa Cruz Biotechnology
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KRTAP12-3 CRISPR Activation Plasmid (h2) - sc-415733-ACT-2 from Santa Cruz Biotechnology
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KRTAP12-3 Lentiviral Activation Particles (h) - sc-415733-LAC from Santa Cruz Biotechnology
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KRTAP12-3 Lentiviral Activation Particles (h2) - sc-415733-LAC-2 from Santa Cruz Biotechnology
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KRTAP12-3 siRNA (h) - sc-91511 from Santa Cruz Biotechnology
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KRTAP12-3 shRNA Plasmid (h) - sc-91511-SH from Santa Cruz Biotechnology
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KRTAP12-3 shRNA (h) Lentiviral Particles - sc-91511-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN11430 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11430 from Sigma-Aldrich
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KRTAP12-3 siRNA (Human) - CRJ7719 from Cohesion Biosciences
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shRNA set against Human KRTAP12-3(NM_198697.2) - SHH138773 from Creative biogene
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Human KRTAP12-3 siRNA - orb278220 from Biorbyt
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KRTAP12-3 shRNA Plasmid (Human) - CHJ7719 from Cohesion Biosciences
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KRTAP12-3 miRNA 3'UTR clone - MiUTR1H-05489 from Creative biogene
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