PSAP

Gene Symbol PSAP
Entrez Gene 5660
Alt Symbol GLBA, SAP1
Species Human
Gene Type protein-coding
Description prosaposin
Other Description proactivator polypeptide|sphingolipid activator protein-1
Swissprots P07292 Q53Y86 P78547 Q92740 P78541 P07602 Q92742 Q92741 Q6IBQ6 P15793 P78546 Q92739 P78558 P78538
Accessions AAC64921 AAG31635 CAA40391 CAA40392 CCQ43188 EAW54436 EAW54437 EAW54438 P07602 AB209776 BAD93013 AK057878 AK129790 AK223290 BAD97010 AK293672 BAG57116 AK299184 BAG61229 AK307721 BC001503 AAH01503 BC004275 AAH04275 BC007612 AAH07612 BC091483 AAH91483 BT006849 AAP35495 CR456746 CAG33027 D00422 BAA00321 DQ587608 DQ893009 ABM83935 DQ896255 ABM87254 J03015 AAB59494 J03077 AAA52560 M12710 M32221 AAA60303 M60255 AAA36594 M60257 AAA36595 M60258 AAA36596 M81355 NM_001042465 NP_001035930 NM_001042466 NP_001035931 NM_002778 NP_002769
Function Saposins are specific low-molecular mass non-enzymic proteins, they participate in the lysosomal degradation of sphingolipids, which takes place by the sequential action of specific hydrolases.
Subcellular Location Lysosome {ECO:0000269|PubMed:14657016, ECO:0000269|PubMed:21835174}.
Top Pathways Lysosome

Human PSAP full length protein - ab167924 from Abcam

Category Protein
Source HEK 293 cells
Species Human
12% SDS-PAGE analysis of ab167924 Lane 1: reduced and boiled sample, 2.5µg/lane Lane 2: non-reduced and non-boiled sample, 2.5µg/lane The ~66 kDa band corresponds to whole PSAP (prosaposin) molecule that consists of four saposin units. The individual saposins naturally cleave off the prosaposin which results in ~15, ~35 and ~50 kDa fragments of mono-, di- and trisaposins, respectively.

Human PSAP full length protein - ab132585 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE analysis of ab132585 stained with Coomassie Blue.

Human PSAP full length protein - ab132586 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE analysis of ab132586 stained with Coomassie Blue.

Human PSAP full length protein - ab203534 from Abcam

Category Protein
Source HEK 293 cells
Species Human
12% SDS-PAGE analysis of ab203534. Lane 1: Reduced and boiled sample, 2.5 μg/lane Lane 2: Non-reduced and non-boiled sample, 2.5 μg/lane The ~66KDa band corresponds to whole PSAP molecule that consists of four saposin units. The individual saposins naturally cleave off the prosaposin which results in ~15, ~35 and ~50 kDa fragments of mono-, di- and trisaposins, respectively.

Human PSAP full length protein - ab168060 from Abcam

Category Protein
Source E. coli
Species Human

Human PSAP protein fragment - ab93982 from Abcam

Category Protein
Source E. coli
Species Human
The image shows an electrophoretic assay performed using an Agilent 5100 ALP. In some images coloured control bands can be seen at 15 kDa (green) and/or 240 kDa (purple). The protein-specific band is blue.

PSAP peptide - ab106466 from Abcam

Category Peptide

SAP-Antibody-Center-E300-Blocking-Peptide - BP7398c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Recombinant human Proactivator polypeptide (OPCA00191) - OPCA00191 from Aviva Systems Biology

Category Protein
Prices $220.00
Sizes 50 µg
Species Human

Human PSAP protein - orb244465 from Biorbyt

Category Protein
Prices $340.00, $629.00, $1,003.00, $1,556.00
Sizes 50 μg, 200 μg, 500 μg, 1 mg
Species Human

PSAP - H00005660-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

PSAP - H00005660-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

PSAP - H00005660-P02 from Acris Antibodies

Category Protein
Prices $370.00
Sizes 10 µg
Species Human

PSAP - H00005660-P02-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

PSAP - H00005660-P02-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

PSAP fusion protein - Ag13264 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

PSAP fusion protein - ag13265 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

PSAP fusion protein - Ag13266 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

PSAP fusion protein - Ag1194 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

PSAP fusion protein - ag13263 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

Human PSAP Antibody - GWB-ASE866 from Genway Biotech

Category Protein
Prices $180.00, $300.00
Sizes 50 μg, 100 μg
Source Rabbit
Species Human

Recombinant Human PSAP, His-tagged - PSAP-30347TH from Creative Biomart

Category Protein
Source E. coli

Recombinant Prosaposin (PSAP) - RPC756Hu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Human

Recombinant Human Proactivator polypeptide - CSB-EP018836HU CSB-BP018836HU CSB-MP018836HU from Cusabio

Category Protein
Source E.coli or Baculovirus or Mammalian cell
Species Human

Recombinant Human Proactivator polypeptide - CSB-EP018836HU from Cusabio

Category Protein
Source E.coli
Species Human
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