CTSD

Gene Symbol	CTSD
Entrez Gene	1509
Alt Symbol	CLN10, CPSD, HEL-S-130P
Species	Human
Gene Type	protein-coding
Description	cathepsin D
Other Description	ceroid-lipofuscinosis, neuronal 10|epididymis secretory sperm binding protein Li 130P|lysosomal aspartyl peptidase|lysosomal aspartyl protease
Swissprots	Q6IB57 P07339
Accessions	AAA16314 AAA51922 AAD13868 AAD14156 EAX02461 EAX02462 EAX02463 P07339 AK130178 BC001574 BC016320 AAH16320 BM762986 BM976200 BT006910 AAP35556 BT020155 AAV38957 CR456947 CAG33228 DQ893547 ABM84473 DQ893878 ABM84804 EU794598 ACJ13652 M11233 AAB59529 X05344 CAA28955 NM_001909 NP_001900
Function	Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.
Subcellular Location	Lysosome. Melanosome. Secreted, extracellular space. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. In aortic samples, detected as an extracellular protein loosely bound to the matrix (PubMed:20551380). {ECO:0000269|PubMed:20551380}.
Tissue Specificity	Expressed in the aorta extrcellular space (at protein level). {ECO:0000269|PubMed:20551380}.
Top Pathways	Lysosome, Tuberculosis, Sphingolipid signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CTSD-Over-expression-Lysate - LY11486a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

CTSD 293T Cell Transient Overexpression Lysate(Denatured) - H00001509-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

CTSD 293 Cell Lysate - 400692 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

Cathepsin D Overexpression Lysate (Denatured) - H00001509-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Cathepsin D Overexpression Lysate (Native) - NBL1-09590 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

cathepsin D (h2): 293T Lysate - sc-170717 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

CTSD Over-expression Lysate Product - GWB-68EAA0 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Human Cathepsin D / CTSD HEK293 Cell Lysate (WB positive control) - 12517-H08HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human Cathepsin D Human Cells Transfected Lysate (positive control) (denatured) - orb173979 from Biorbyt Category Cell Lysate Prices $425.00 Sizes 300 μg Species Human

Panoply™ Human CTSD Knockdown Stable Cell Line - CSC-DC003817 from Creative biogene Category Cell Line Species Human

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