CTSD

Gene Symbol	CTSD
Entrez Gene	1509
Alt Symbol	CLN10, CPSD, HEL-S-130P
Species	Human
Gene Type	protein-coding
Description	cathepsin D
Other Description	ceroid-lipofuscinosis, neuronal 10|epididymis secretory sperm binding protein Li 130P|lysosomal aspartyl peptidase|lysosomal aspartyl protease
Swissprots	Q6IB57 P07339
Accessions	AAA16314 AAA51922 AAD13868 AAD14156 EAX02461 EAX02462 EAX02463 P07339 AK130178 BC001574 BC016320 AAH16320 BM762986 BM976200 BT006910 AAP35556 BT020155 AAV38957 CR456947 CAG33228 DQ893547 ABM84473 DQ893878 ABM84804 EU794598 ACJ13652 M11233 AAB59529 X05344 CAA28955 NM_001909 NP_001900
Function	Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.
Subcellular Location	Lysosome. Melanosome. Secreted, extracellular space. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. In aortic samples, detected as an extracellular protein loosely bound to the matrix (PubMed:20551380). {ECO:0000269|PubMed:20551380}.
Tissue Specificity	Expressed in the aorta extrcellular space (at protein level). {ECO:0000269|PubMed:20551380}.
Top Pathways	Lysosome, Tuberculosis, Sphingolipid signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-CTSD-cDNA-Clone - DC04292 from Abgent, a WuXi AppTec company Prices $556.20 Sizes 10 µg Species Human Accession BC016320

CTSD - MBS1274161 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC016320

Human CTSD ORF Clone(NM_001909.4) - CDCL160081 from Creative Biomart Species Human Accession NM_001909.4

Human CTSD Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG12517-G-N from Sino Biological Species Human Accession NM_001909.4

Human CTSD ORF Clone (BC016320) - CDCS410513 from Creative biogene Species Human Accession P07339

Human Cathepsin D/CTSD Gene ORF cDNA clone in cloning vector - HG12517-U from Sino Biological Species Human

Human Cathepsin D/CTSD Gene ORF cDNA clone expression plasmid - HG12517-UT from Sino Biological Species Human

Human Cathepsin D/CTSD Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG12517-ACG from Sino Biological Species Human

Human Cathepsin D/CTSD Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG12517-ACR from Sino Biological Species Human

Human Cathepsin D/CTSD Gene ORF cDNA clone expression plasmid, C-Flag tag - HG12517-CF from Sino Biological Species Human

Human Cathepsin D/CTSD Gene ORF cDNA clone expression plasmid, C-His tag - HG12517-CH from Sino Biological Species Human

Human Cathepsin D/CTSD Gene ORF cDNA clone expression plasmid, C-Myc tag - HG12517-CM from Sino Biological Species Human

Human Cathepsin D/CTSD Gene ORF cDNA clone expression plasmid, C-HA tag - HG12517-CY from Sino Biological Species Human

Human Cathepsin D/CTSD Gene ORF cDNA clone expression plasmid, N-Flag tag - HG12517-NF from Sino Biological Species Human

Human Cathepsin D/CTSD Gene ORF cDNA clone expression plasmid, N-His tag - HG12517-NH from Sino Biological Species Human

Human Cathepsin D/CTSD Gene ORF cDNA clone expression plasmid, N-Myc tag - HG12517-NM from Sino Biological Species Human

Human Cathepsin D/CTSD Gene ORF cDNA clone expression plasmid, N-HA tag - HG12517-NY from Sino Biological Species Human

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