| Gene Symbol |
ANKRD13D
|
| Entrez Gene |
338692
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ankyrin repeat domain 13 family, member D
|
| Other Description |
ankyrin repeat domain-containing protein 13D
|
| Swissprots |
Q86SU1 D6RCN6 Q6ZVD0 Q6ZTN6 Q0VAK0 Q0VGC3
|
| Accessions |
EAW74583 EAW74584 EAW74585 EAW74586 Q6ZTN6 AK027313 BAG51301 AK057566 AK057681 BAG51952 AK091614 AK096277 AK124721 BAC85932 AK126438 BAC86550 BC044239 AAH44239 BC110419 AAI10420 BC121024 AAI21025 BC121025 AAI21026 DA870287 DB460018 XM_011544985 XP_011543287 XM_011544986 XP_011543288 XM_011544987 XP_011543289 XM_011544988 XP_011543290 XR_428913 XR_949901 XR_949902 NM_207354 NP_997237 NR_030767
|
| Function |
Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand- activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane. {ECO:0000269|PubMed:22298428}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:22298428}. Late endosome {ECO:0000269|PubMed:22298428}. Note=Interaction with EGFR may enhance association with the cell membrane.
|