Gene Symbol | ANKRD13D |
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Entrez Gene | 338692 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | ankyrin repeat domain 13 family, member D |
Other Description | ankyrin repeat domain-containing protein 13D |
Swissprots | Q86SU1 D6RCN6 Q6ZVD0 Q6ZTN6 Q0VAK0 Q0VGC3 |
Accessions | EAW74583 EAW74584 EAW74585 EAW74586 Q6ZTN6 AK027313 BAG51301 AK057566 AK057681 BAG51952 AK091614 AK096277 AK124721 BAC85932 AK126438 BAC86550 BC044239 AAH44239 BC110419 AAI10420 BC121024 AAI21025 BC121025 AAI21026 DA870287 DB460018 XM_011544985 XP_011543287 XM_011544986 XP_011543288 XM_011544987 XP_011543289 XM_011544988 XP_011543290 XR_428913 XR_949901 XR_949902 NM_207354 NP_997237 NR_030767 |
Function | Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand- activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane. {ECO:0000269|PubMed:22298428}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:22298428}. Late endosome {ECO:0000269|PubMed:22298428}. Note=Interaction with EGFR may enhance association with the cell membrane. |
ANKRD13D CRISPR/Cas9 KO Plasmid (h) - sc-415493 from Santa Cruz Biotechnology
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ANKRD13D HDR Plasmid (h) - sc-415493-HDR from Santa Cruz Biotechnology
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ANKRD13D Double Nickase Plasmid (h) - sc-415493-NIC from Santa Cruz Biotechnology
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ANKRD13D Double Nickase Plasmid (h2) - sc-415493-NIC-2 from Santa Cruz Biotechnology
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ANKRD13D CRISPR Activation Plasmid (h) - sc-415493-ACT from Santa Cruz Biotechnology
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ANKRD13D CRISPR Activation Plasmid (h2) - sc-415493-ACT-2 from Santa Cruz Biotechnology
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ANKRD13D Lentiviral Activation Particles (h) - sc-415493-LAC from Santa Cruz Biotechnology
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ANKRD13D Lentiviral Activation Particles (h2) - sc-415493-LAC-2 from Santa Cruz Biotechnology
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ANKRD13D siRNA (h) - sc-96992 from Santa Cruz Biotechnology
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ANKRD13D shRNA Plasmid (h) - sc-96992-SH from Santa Cruz Biotechnology
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ANKRD13D shRNA (h) Lentiviral Particles - sc-96992-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN3178 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3178 from Sigma-Aldrich
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ANKRD13D siRNA (Human) - CRJ7251 from Cohesion Biosciences
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ANKRD13D - MBS8217399 from MyBioSource
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shRNA set against Human ANKRD13D (NM_207354.2) - SHH236610 from Creative biogene
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Human ANKRD13D siRNA - orb277752 from Biorbyt
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ANKRD13D shRNA Plasmid (Human) - CHJ7251 from Cohesion Biosciences
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ANKRD13D miRNA 3'UTR clone - MiUTR3H-13454 from Creative biogene
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