CCL22

Gene Symbol	CCL22
Entrez Gene	6367
Alt Symbol	A-152E5.1, ABCD-1, DC/B-CK, MDC, SCYA22, STCP-1
Species	Human
Gene Type	protein-coding
Description	chemokine (C-C motif) ligand 22
Other Description	C-C motif chemokine 22|CC chemokine STCP-1|MDC(1-69)|macrophage-derived chemokine|small inducible cytokine A22|small inducible cytokine subfamily A (Cys-Cys), member 22|small-inducible cytokine A22|stimulated T cell chemotactic protein 1|stimulated T-cell chemotactic protein 1
Swissprots	A0N0Q6 O00626 B2R4W2
Accessions	AAC24306 ABK41947 EAW82918 O00626 AK311970 BAG34909 BC027952 AAH27952 DA815965 DB154173 DQ890922 ABM81848 DQ893311 ABM84237 DQ894072 ABM84998 DQ896625 ABM87624 EU176526 ABW03327 U83171 AAB58360 U83239 AAB53372 NM_002990 NP_002981
Function	May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4. Processed forms MDC(3-69), MDC(5-69) and MDC(7-69) seem not be active.
Subcellular Location	Secreted.
Tissue Specificity	Highly expressed in macrophage and in monocyte-derived dendritic cells, and thymus. Also found in lymph node, appendix, activated monocytes, resting and activated macrophages. Lower expression in lung and spleen. Very weak expression in small intestine. In lymph node expressed in a mature subset of Langerhans' cells (CD1a+ and CD83+). Expressed in Langerhans' cell histiocytosis but not in dermatopathic lymphadenopathy. Expressed in atopic dermatitis, allergic contact dermatitis skin, and psoriasis, in both the epidermis and dermis. {ECO:0000269|PubMed:11241286}.
Top Pathways	Cytokine-cytokine receptor interaction, Chemokine signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MDC (CCL22) Human ELISA Kit - ab100591 from Abcam Category ELISA Kit Prices $489.00 Sizes 1 x 96 tests Sensitivity < 1.5 pg/ml Range 1.65 pg/ml - 400 pg/ml

MDC (CCL22) Human SimpleStep ELISA™ Kit - ab179885 from Abcam Category ELISA Kit Prices $484.00 Sizes 1 x 96 tests Sensitivity 3.79 pg/ml Range 15.6 pg/ml - 1000 pg/ml

Human CCL22 / MDC ELISA Kit (Sandwich ELISA) - LS-F5150 from LifeSpan Bioscience Category ELISA Kit Prices $470.00 Sizes 1 plate Sensitivity 30 pg/ml Range 0.549-133.3 pg/ml

Rat CCL22 / MDC ELISA Kit (Sandwich ELISA) - LS-F5527 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 8.45 pg/ml Range 0.549-133.3 pg/ml

Human CCL22 / MDC ELISA Kit (Sandwich ELISA) - LS-F2501 from LifeSpan Bioscience Category ELISA Kit Prices $510.00 Sizes 1 plate Sensitivity 1 pg/ml Range 0.549-133.3 pg/ml

Mouse CCL22 / MDC ELISA Kit (Sandwich ELISA) - LS-F2502 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Sensitivity 1 pg/ml Range 0.549-133.3 pg/ml

Mouse CCL22 / MDC ELISA Kit (Sandwich ELISA) - LS-F4950 from LifeSpan Bioscience Category ELISA Kit Prices $480.00 Sizes 1 plate Sensitivity 5.8 pg/ml Range 0.549-133.3 pg/ml

Bovine CCL22 / MDC ELISA Kit (Sandwich ELISA) - LS-F6151 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 5.4 pg/ml Range 0.549-133.3 pg/ml

Human CCL22 / MDC ELISA Kit (Sandwich ELISA) - LS-F461 from LifeSpan Bioscience Category ELISA Kit Prices $460.00, $840.00, $1,960.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 0.549 pg/ml Range 0.549-133.3 pg/ml

Mouse CCL22 / MDC ELISA Kit (Sandwich ELISA) - LS-F502 from LifeSpan Bioscience Category ELISA Kit Prices $460.00, $840.00, $1,960.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 2.458 pg/ml Range 0.549-133.3 pg/ml

Human CCL22 / MDC ELISA Kit (Sandwich ELISA) - LS-F1019 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.549-133.3 pg/ml

Mouse CCL22 / MDC ELISA Kit (Sandwich ELISA) - LS-F974 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.549-133.3 pg/ml

Human CCL22 / MDC ELISA Kit (Sandwich ELISA) - LS-F9986 from LifeSpan Bioscience Category ELISA Kit Prices $570.00 Sizes 1 plate Sensitivity 10.324 pg/ml Range 0.549-133.3 pg/ml

Mouse CCL22 / MDC ELISA Kit (Sandwich ELISA) - LS-F9987 from LifeSpan Bioscience Category ELISA Kit Prices $630.00 Sizes 1 plate Sensitivity 23.672 pg/ml Range 0.549-133.3 pg/ml

Human MDC / CCL22 ELISA Kit - RAB0064 from Sigma-Aldrich Category ELISA Kit Prices $423.50 Sizes 1 kt

CCL22/MDC BioAssay™ ELISA Kit, Human - 143750 from USBiological Life Science Category ELISA Kit Sensitivity < 1 pg/ml Range 31.2pg/ml-2000pg/ml

Mouse CCL22/MDC DuoSet ELISA - DY439 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 7.81 - 500 pg/mL

Human CCL22/MDC Quantikine ELISA Kit - DMD00 from R&D Systems Category ELISA Kit Prices $509.00 Sizes 1 kit Sensitivity 62.5 pg/mL Range 125.0 - 4,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma)

Mouse CCL22/MDC Quantikine ELISA Kit - MCC220 from R&D Systems Category ELISA Kit Prices $277.82, $479.00 Sizes 1 kit, 1 kit Sensitivity 1.8 pg/mL Range 7.8 - 500 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma)

Human CCL22/MDC DuoSet ELISA - DY336 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 7.81 - 500 pg/mL

Human MDC ELISA kit - 55R-2065 from Fitzgerald Category ELISA Kit Prices $505.00 Sizes 96 tests

MDC ELISA Kit (Human) : 96 Wells (OKAG00203) - OKAG00203 from Aviva Systems Biology Category ELISA Kit Prices $390.00 Sizes 96 wells Sensitivity 8 pg/mL Range 8-500 pg/mL

Human CCL22 ELISA Kit - abx056041 from Abbexa Category ELISA Kit

Human Macrophage-Derived Chemokine ELISA Kit - abx053843 from Abbexa Category ELISA Kit

C-C motif chemokine 22, CCL22, Human, ELISA Kit - E0091h from ARP American Research Products Category ELISA Kit Prices $476.00 Sizes 96 t Range 0.156-10 ng/mL

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