A1CF

Gene Symbol	A1CF
Entrez Gene	29974
Alt Symbol	ACF, ACF64, ACF65, APOBEC1CF, ASP
Species	Human
Gene Type	protein-coding
Description	APOBEC1 complementation factor
Other Description	APOBEC-1 stimulating protein|apo-B RNA editing protein|apobec-1 complementation factor (ACF) (ASP)
Swissprots	Q9NZD3 A8K7G7 A1L4F2 Q9NXC9 Q5SZQ0 Q9NQ93 Q9NQ94 Q9NQX8 Q9NQX9 B7ZM14
Accessions	EAW54133 EAW54134 EAW54135 EAW54136 EAW54137 EAW54138 Q9NQ94 AF209192 AAF34824 AF271789 AAF76221 AF271790 AAF76222 AJ272078 CAB94754 AJ272079 CAB94755 AK000324 BAA91086 AK130022 AK291982 BAF84671 AK303801 BAG64755 BC022263 BC054873 AAH54873 BC130519 AAI30520 BC144194 BC144196 AAI44197 BG188383 CR749831 XM_005269718 XP_005269775 XM_005269720 XP_005269777 XM_011539729 XP_011538031 XM_011539730 XP_011538032 NM_001198818 NP_001185747 NM_001198819 NP_001185748 NM_001198820 NP_001185749 NM_014576 NP_055391 NM_138932 NP_620310 NM_138933 NP_620311
Function	Essential component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in APOB mRNA. Binds to APOB mRNA and is probably responsible for docking the catalytic subunit, APOBEC1, to the mRNA to allow it to deaminate its target cytosine. The complex also protects the edited APOB mRNA from nonsense-mediated decay. {ECO:0000269|PubMed:10669759, ECO:0000269|PubMed:10781591, ECO:0000269|PubMed:12881431}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:12881431}. Endoplasmic reticulum {ECO:0000250}. Cytoplasm {ECO:0000269|PubMed:12881431}. Note=Predominantly nuclear where it localizes to heterochromatin. Also cytoplasmic where it is found at the outer surface of the endoplasmic reticulum (By similarity). Shuttles between the nucleus and cytoplasm. May be transported into the nucleus by the nuclear import protein TNPO2/TRN2 or by APOBEC1. {ECO:0000250}.
Tissue Specificity	Widely expressed with highest levels in brain, liver, pancreas, colon and spleen. {ECO:0000269|PubMed:10669759}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

A1CF / ACF Antibody Blocking Peptide - LS-E392 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

A1CF / ACF Antibody Blocking Peptide - LS-E14945 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

A1CF / ACF Antibody Blocking Peptide - LS-E15094 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ACF-Antibody-C-term-Blocking-peptide - BP10670b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

A1CF Blocking Peptide - 33R-5962 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

A1CF Blocking Peptide - 33R-2286 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

A1CF fusion protein - Ag22975 from Proteintech Group Category Protein Prices $199.00 Sizes 50 Source E. coli -derived, PET30a Species Human

Recombinant Apobec 1 Complementation Factor (ACF) - RPA426Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Human APOBEC1 complementation factor(A1CF) - CSB-YP001002HU CSB-EP001002HU CSB-BP001002HU CSB-MP001002HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

APOBEC1 complementation factor (transcript variant 2) - TP316861 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

APOBEC1 complementation factor (transcript variant 3) - TP316911 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

APOBEC1 complementation factor (A1CF) , Recombinant Protein - MBS1416439 from MyBioSource Category Protein Prices $2,330.00, $2,330.00, $2,755.00, $2,755.00 Sizes 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

A1CF Recombinant Protein (OPCD01028) - OPCD01028 from Aviva Systems Biology Category Protein Source E.coli Species Human

Recombinant Human A1CF Protein, His-tagged - A1CF-641H from Creative Biomart Category Protein Source E. coli Species Human

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