| Gene Symbol |
SLC19A3
|
| Entrez Gene |
80704
|
| Alt Symbol |
BBGD, THMD2, THTR2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 19 (thiamine transporter), member 3
|
| Other Description |
solute carrier family 19, member 3|thTr-2|thiamine transporter 2
|
| Swissprots |
Q9BZV2
|
| Accessions |
AAX93157 EAW70875 EAW70876 Q9BZV2 AF271633 AAG53879 AF283317 AAK69539 AI056985 AK301490 BAH13497 AK312464 BAG35371 BC032014 AAH32014 DQ892411 ABM83337 DQ895625 ABM86551 XM_005246874 XP_005246931 XM_006712779 XP_006712842 XM_011511931 XP_011510233 XM_011511932 XP_011510234 XM_011511933 XP_011510235 NM_025243 NP_079519
|
| Function |
Mediates high affinity thiamine uptake, propably via a proton anti-port mechanism. Has no folate transport activity. {ECO:0000269|PubMed:11731220}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Widely expressed but most abundant in placenta, kidney and liver. {ECO:0000269|PubMed:11136550, ECO:0000269|PubMed:15871139}.
|
| Top Pathways |
Vitamin digestion and absorption
|