Gene Symbol | SLC19A3 |
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Entrez Gene | 80704 |
Alt Symbol | BBGD, THMD2, THTR2 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 19 (thiamine transporter), member 3 |
Other Description | solute carrier family 19, member 3|thTr-2|thiamine transporter 2 |
Swissprots | Q9BZV2 |
Accessions | AAX93157 EAW70875 EAW70876 Q9BZV2 AF271633 AAG53879 AF283317 AAK69539 AI056985 AK301490 BAH13497 AK312464 BAG35371 BC032014 AAH32014 DQ892411 ABM83337 DQ895625 ABM86551 XM_005246874 XP_005246931 XM_006712779 XP_006712842 XM_011511931 XP_011510233 XM_011511932 XP_011510234 XM_011511933 XP_011510235 NM_025243 NP_079519 |
Function | Mediates high affinity thiamine uptake, propably via a proton anti-port mechanism. Has no folate transport activity. {ECO:0000269|PubMed:11731220}. |
Subcellular Location | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
Tissue Specificity | Widely expressed but most abundant in placenta, kidney and liver. {ECO:0000269|PubMed:11136550, ECO:0000269|PubMed:15871139}. |
Top Pathways | Vitamin digestion and absorption |
THTR2 CRISPR/Cas9 KO Plasmid (h) - sc-407588 from Santa Cruz Biotechnology
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THTR2 HDR Plasmid (h) - sc-407588-HDR from Santa Cruz Biotechnology
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THTR2 Double Nickase Plasmid (h) - sc-407588-NIC from Santa Cruz Biotechnology
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THTR2 Double Nickase Plasmid (h2) - sc-407588-NIC-2 from Santa Cruz Biotechnology
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THTR2 CRISPR Activation Plasmid (h) - sc-407588-ACT from Santa Cruz Biotechnology
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THTR2 CRISPR Activation Plasmid (h2) - sc-407588-ACT-2 from Santa Cruz Biotechnology
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THTR2 Lentiviral Activation Particles (h) - sc-407588-LAC from Santa Cruz Biotechnology
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THTR2 Lentiviral Activation Particles (h2) - sc-407588-LAC-2 from Santa Cruz Biotechnology
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THTR2 siRNA (h) - sc-95016 from Santa Cruz Biotechnology
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THTR2 shRNA Plasmid (h) - sc-95016-SH from Santa Cruz Biotechnology
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THTR2 shRNA (h) Lentiviral Particles - sc-95016-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU004301 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2497 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2497 from Sigma-Aldrich
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SLC19A3 siRNA (Human) - CRJ2880 from Cohesion Biosciences
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SLC19A3 RNAi - H00080704-R01 from Novus Biologicals
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SLC19A3 - MBS8240774 from MyBioSource
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shRNA set against Human SLC19A3 (NM_025243.3) - SHH408884 from Creative biogene
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SLC19A3 shRNA Plasmid (Human) - CHJ2880 from Cohesion Biosciences
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SLC19A3 miRNA 3'UTR clone - MiUTR1H-09451 from Creative biogene
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