MS4A2

Gene Symbol	MS4A2
Entrez Gene	2206
Alt Symbol	APY, ATOPY, FCER1B, FCERI, IGEL, IGER, IGHER, MS4A1
Species	Human
Gene Type	protein-coding
Description	membrane-spanning 4-domains, subfamily A, member 2
Other Description	Fc fragment of IgE, high affinity I, receptor for; beta polypeptide|High affinity immunoglobulin epsilon receptor beta-subunit (FcERI) (IgE Fc receptor, beta-subunit) (Fc epsilon receptor I beta-chain)|high affinity IgE receptor beta subunit|high affinity immunoglobulin epsilon receptor subunit beta|igE Fc receptor subunit beta|immunoglobulin E receptor, high affinity, beta polypeptide
Swissprots	Q54A81 Q01362
Accessions	AAA60269 BAB17032 BAC66486 EAW73865 Q01362 AK304487 BAG65297 AK310142 BC074800 AAH74800 BC074843 AAH74843 D10583 BAA01440 DA972757 GD138492 JF411082 AEA50999 X66187 CAA46955 XM_005273846 XP_005273903 XM_011544850 XP_011543152 NM_000139 NP_000130 NM_001256916 NP_001243845 NM_001142303
Function	High affinity receptor that binds to the Fc region of immunoglobulins epsilon. Aggregation of FCER1 by multivalent antigens is required for the full mast cell response, including the release of preformed mediators (such as histamine) by degranulation and de novo production of lipid mediators and cytokines. Also mediates the secretion of important lymphokines. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators responsible for the manifestations of allergy.
Subcellular Location	Membrane; Multi-pass membrane protein.
Tissue Specificity	Found on the surface of mast cells and basophils.
Top Pathways	Fc epsilon RI signaling pathway, Asthma, Sphingolipid signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MS4A2 overexpression lysate - LY400048 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

MS4A2 293 Cell Lysate - 400143 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

Fc epsilon RI beta/MS4A2 Overexpression Lysate (Native) - NBL1-13315 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

MS4A2 Over-expression Lysate Product - GWB-966B70 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Fc epsilon RI beta/MS4A2 Overexpression Lysate (Denatured) - H00002206-T02 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Panoply™ Human MS4A2 Knockdown Stable Cell Line - CSC-DC009804 from Creative biogene Category Cell Line Species Human

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