KCNQ5

Gene Symbol	KCNQ5
Entrez Gene	56479
Alt Symbol	Kv7.5
Species	Human
Gene Type	protein-coding
Description	potassium channel, voltage gated KQT-like subfamily Q, member 5
Other Description	KQT-like 5|potassium channel protein|potassium channel subunit alpha KvLQT5|potassium voltage-gated channel subfamily KQT member 5|potassium voltage-gated channel, KQT-like subfamily, member 5|voltage-gated potassium channel subunit Kv7.5
Swissprots	Q9NYA6 F5GZV0 Q17RE1 A8MSQ5 Q86W40 A6NKT6 B7ZL37 B4DS33 Q5VVP3 Q9NR82 A6PVT6 Q9NRN0 B5MC83
Accessions	CAC88112 EAW48782 EAW48783 Q9NR82 AF202977 AAF69797 AF249278 AAF91335 AF263835 AAF73446 AK299550 BAG61495 AK299741 BAG61636 AK316070 BAH14441 BC050689 AAH50689 BC117359 AAI17360 BC143554 AAI43555 BC143555 BF513800 DA801374 XM_011535944 XP_011534246 XM_011535945 XP_011534247 NM_001160130 NP_001153602 NM_001160132 NP_001153604 NM_001160133 NP_001153605 NM_001160134 NP_001153606 NM_019842 NP_062816
Function	Probably important in the regulation of neuronal excitability. Associates with KCNQ3 to form a potassium channel which contributes to M-type current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons. May contribute, with other potassium channels, to the molecular diversity of a heterogeneous population of M-channels, varying in kinetic and pharmacological properties, which underlie this physiologically important current. Insensitive to tetraethylammonium, but inhibited by barium, linopirdine and XE991. Activated by niflumic acid and the anticonvulsant retigabine. Muscarine suppresses KCNQ5 current in Xenopus oocytes in which cloned KCNQ5 channels were coexpressed with M(1) muscarinic receptors.
Subcellular Location	Membrane; Multi-pass membrane protein.
Tissue Specificity	Strongly expressed in brain and skeletal muscle. In brain, expressed in cerebral cortex, occipital pole, frontal lobe and temporal lobe. Lower levels in hippocampus and putamen. Low to undetectable levels in medulla, cerebellum and thalamus.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

KCNQ5 (C-17) - sc-18048 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

KCNQ5 (H-170) - sc-50416 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

KCNQ5 (N-13) - sc-18046 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-KCNQ5 antibody - ab96707 from Abcam Prices $370.00 Sizes 50 µl Host Rabbit Clonality Polyclonal

Anti-KCNQ5 antibody - ab130382 from Abcam Prices $359.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-KCNQ5 antibody - ab57634 from Abcam Prices $370.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-KCNQ5 antibody - C-terminal - ab191136 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-KCNQ5 antibody - Carboxyterminal end - ab66740 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-KCNQ5 Antibody (aa938-951) - LS-C112722 from LifeSpan Bioscience Prices $335.00 Sizes 100 µg Host Goat Clonality Polyclonal

Anti-KCNQ5 Antibody (aa781-809, AP) - LS-C236771 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KCNQ5 Antibody (C-Terminus) - LS-C144793 from LifeSpan Bioscience Prices $365.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-KCNQ5 Antibody (aa781-809, Biotin) - LS-C236774 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KCNQ5 Antibody (aa781-809, APC) - LS-C236772 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KCNQ5 Antibody (aa781-809, FITC) - LS-C236775 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KCNQ5 Antibody (aa781-809, PE) - LS-C236776 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KCNQ5 Antibody (aa637-686) - LS-C291358 from LifeSpan Bioscience Prices $315.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-KCNQ5 Antibody (aa781-809, Azide-free, HRP) - LS-C249312 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KCNQ5 Antibody (aa619-668) - LS-C292119 from LifeSpan Bioscience Prices $315.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-KCNQ5 Antibody (aa780-809) - LS-C322406 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KCNQ5 Antibody (aa833-933) - LS-C308603 from LifeSpan Bioscience Prices $455.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-KCNQ5 Antibody (aa575-624) - LS-C110213 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-KCNQ5 Antibody (aa458-714) - LS-C185769 from LifeSpan Bioscience Prices $335.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-KCNQ5 Antibody (aa781-809) - LS-C165447 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-KCNQ5 Antibody (aa619-633) - LS-C313524 from LifeSpan Bioscience Prices $305.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Kv7.5 Antibody - NBP1-32309 from Novus Biologicals Prices $349.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

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