KCNQ5

Gene Symbol	KCNQ5
Entrez Gene	56479
Alt Symbol	Kv7.5
Species	Human
Gene Type	protein-coding
Description	potassium channel, voltage gated KQT-like subfamily Q, member 5
Other Description	KQT-like 5|potassium channel protein|potassium channel subunit alpha KvLQT5|potassium voltage-gated channel subfamily KQT member 5|potassium voltage-gated channel, KQT-like subfamily, member 5|voltage-gated potassium channel subunit Kv7.5
Swissprots	Q9NYA6 F5GZV0 Q17RE1 A8MSQ5 Q86W40 A6NKT6 B7ZL37 B4DS33 Q5VVP3 Q9NR82 A6PVT6 Q9NRN0 B5MC83
Accessions	CAC88112 EAW48782 EAW48783 Q9NR82 AF202977 AAF69797 AF249278 AAF91335 AF263835 AAF73446 AK299550 BAG61495 AK299741 BAG61636 AK316070 BAH14441 BC050689 AAH50689 BC117359 AAI17360 BC143554 AAI43555 BC143555 BF513800 DA801374 XM_011535944 XP_011534246 XM_011535945 XP_011534247 NM_001160130 NP_001153602 NM_001160132 NP_001153604 NM_001160133 NP_001153605 NM_001160134 NP_001153606 NM_019842 NP_062816
Function	Probably important in the regulation of neuronal excitability. Associates with KCNQ3 to form a potassium channel which contributes to M-type current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons. May contribute, with other potassium channels, to the molecular diversity of a heterogeneous population of M-channels, varying in kinetic and pharmacological properties, which underlie this physiologically important current. Insensitive to tetraethylammonium, but inhibited by barium, linopirdine and XE991. Activated by niflumic acid and the anticonvulsant retigabine. Muscarine suppresses KCNQ5 current in Xenopus oocytes in which cloned KCNQ5 channels were coexpressed with M(1) muscarinic receptors.
Subcellular Location	Membrane; Multi-pass membrane protein.
Tissue Specificity	Strongly expressed in brain and skeletal muscle. In brain, expressed in cerebral cortex, occipital pole, frontal lobe and temporal lobe. Lower levels in hippocampus and putamen. Low to undetectable levels in medulla, cerebellum and thalamus.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human KCNQ5 protein fragment - ab163381 from Abcam Category Protein Source Wheat germ Species Human

KCNQ5 Antibody Blocking Peptide - LS-E4460 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KCNQ5 Antibody Blocking Peptide - LS-E13520 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KCNQ5 Antibody Blocking Peptide - LS-E27009 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Kv7.5 Protein - H00056479-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

KCNQ5-Antibody-C-term-Blocking-Peptide - BP16776b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

KCNQ5 blocking peptide - GTX88459-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Pig, Rat

KCNQ5 Blocking Peptide - 33R-4980 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

KCNQ5 Peptide - AC21-1834-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

KCNQ5 - H00056479-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

KCNQ5 - H00056479-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

KCNQ5 Peptide - 42-089P from ProSci Category Peptide

KCNQ5, Peptide - MBS426187 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Pig, Dog

Kv7.5, Peptide - MBS659339 from MyBioSource Category Peptide Prices $340.00 Sizes 100 µg Species Human, Rat, Pig, Dog

Kv7.5 Recombinant Protein Antigen - NBP1-82861PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

KCNQ5 Peptide, Human - M34GP08003H from Creative Peptides Category Peptide Source Synthetic. Species Human

KCNQ5 fusion protein - Ag27668 from Proteintech Group Category Protein Source E. coli -derived, PET28a Species Human

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