| Gene Symbol |
Lgals9
|
| Entrez Gene |
16859
|
| Alt Symbol |
AA407335, AI194909, AI265545, LGALS35, Lgals5, gal-9, galectin-9
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
lectin, galactose binding, soluble 9
|
| Other Description |
galectin-9|lectin, galactose binding, soluble 5
|
| Swissprots |
O08572 Q3UKE5 O08573 Q99L83
|
| Accessions |
EDL15597 EDL15598 EDL15599 EDL15600 O08573 AK146044 BAE26856 AK214388 BC003754 AAH03754 CA458877 CA546274 U55060 AAB51189 U55061 AAB51190 NM_001159301 NP_001152773 NM_010708 NP_034838
|
| Function |
Binds galactosides. May play a role in thymocyte- epithelial interactions relevant to the biology of the thymus. Is a ligand for HAVCR2/TIM3. Induces T-helper type 1 lymphocyte (Th1) death (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm. Secreted. Note=May also be secreted by a non-classical secretory pathway.
|
| Tissue Specificity |
Accentuated expression in liver and thymus of embryo, detected in embryonic heart, brain, lung, liver, and kidney. Highly expressed in adult thymus, small intestine, and liver, and to a lesser extent in lung, kidney, spleen, cardiac, and skeletal muscle. Barely detectable in brain and reticulocyte. The isoform Long is expressed exclusively in the small intestine.
|