Gene Symbol | Lgals9 |
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Entrez Gene | 16859 |
Alt Symbol | AA407335, AI194909, AI265545, LGALS35, Lgals5, gal-9, galectin-9 |
Species | Mouse |
Gene Type | protein-coding |
Description | lectin, galactose binding, soluble 9 |
Other Description | galectin-9|lectin, galactose binding, soluble 5 |
Swissprots | O08572 Q3UKE5 O08573 Q99L83 |
Accessions | EDL15597 EDL15598 EDL15599 EDL15600 O08573 AK146044 BAE26856 AK214388 BC003754 AAH03754 CA458877 CA546274 U55060 AAB51189 U55061 AAB51190 NM_001159301 NP_001152773 NM_010708 NP_034838 |
Function | Binds galactosides. May play a role in thymocyte- epithelial interactions relevant to the biology of the thymus. Is a ligand for HAVCR2/TIM3. Induces T-helper type 1 lymphocyte (Th1) death (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm. Secreted. Note=May also be secreted by a non-classical secretory pathway. |
Tissue Specificity | Accentuated expression in liver and thymus of embryo, detected in embryonic heart, brain, lung, liver, and kidney. Highly expressed in adult thymus, small intestine, and liver, and to a lesser extent in lung, kidney, spleen, cardiac, and skeletal muscle. Barely detectable in brain and reticulocyte. The isoform Long is expressed exclusively in the small intestine. |
galectin-9 CRISPR/Cas9 KO Plasmid (m) - sc-421420 from Santa Cruz Biotechnology
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galectin-9 HDR Plasmid (m) - sc-421420-HDR from Santa Cruz Biotechnology
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galectin-9 Double Nickase Plasmid (m) - sc-421420-NIC from Santa Cruz Biotechnology
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galectin-9 Double Nickase Plasmid (m2) - sc-421420-NIC-2 from Santa Cruz Biotechnology
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galectin-9 CRISPR Activation Plasmid (m) - sc-421420-ACT from Santa Cruz Biotechnology
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galectin-9 CRISPR Activation Plasmid (m2) - sc-421420-ACT-2 from Santa Cruz Biotechnology
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galectin-9 Lentiviral Activation Particles (m) - sc-421420-LAC from Santa Cruz Biotechnology
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galectin-9 Lentiviral Activation Particles (m2) - sc-421420-LAC-2 from Santa Cruz Biotechnology
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galectin-9 siRNA (m) - sc-35445 from Santa Cruz Biotechnology
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galectin-9 shRNA Plasmid (m) - sc-35445-SH from Santa Cruz Biotechnology
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galectin-9 shRNA (m) Lentiviral Particles - sc-35445-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU001781 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN34740 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND34740 from Sigma-Aldrich
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LGALS9 siRNA (Mouse) - CRM2336 from Cohesion Biosciences
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shRNA set against Mouse LGALS9 (NM_010708.2) - SHH329871 from Creative biogene
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Mouse LGALS9 siRNA - orb281812 from Biorbyt
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LGALS9 shRNA Plasmid (Mouse) - CHM2336 from Cohesion Biosciences
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