| Gene Symbol |
MAP4K5
|
| Entrez Gene |
11183
|
| Alt Symbol |
GCKR, KHS, KHS1, MAPKKKK5
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
mitogen-activated protein kinase kinase kinase kinase 5
|
| Other Description |
MAPK/ERK kinase kinase kinase 5|MEK kinase kinase 5|MEKKK 5|germinal center kinase-related|kinase homologous to SPS1/STE20
|
| Swissprots |
Q8IYF6 Q9Y4K4
|
| Accessions |
CAV30709 CAV30710 EAW65710 EAW65711 EAW65712 EAW65713 Q9Y4K4 AK124738 BAG54086 AK313612 BAG36375 BC013159 BC036013 AAH36013 CB959746 CB990293 CN343360 DQ894186 ABM85112 U77129 AAB48435 Z25426 CAA80913 XM_006720013 XP_006720076 XM_011536377 XP_011534679 XM_011536378 XP_011534680 XM_011536379 XP_011534681 XM_011536380 XP_011534682 NM_006575 NP_006566 NM_198794 NP_942089
|
| Function |
May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. {ECO:0000269|PubMed:9038372}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:9038372}.
|
| Tissue Specificity |
Ubiquitously expressed in all tissues examined, with high levels in the ovary, testis and prostate. {ECO:0000269|PubMed:9038372}.
|
![Western Blot: MAP4K5 Overexpression Lysate (Adult Normal) [NBL1-12862] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for MAP4K5.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/12061_MAP4K5%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-12862-img0002.jpg)
![Western Blot: MAP4K5 Overexpression Lysate (Adult Normal) [NBP2-07604] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for MAP4K5.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8515_MAP4K5%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-07604-img0001.jpg)
![Western Blot: MAP4K5 Overexpression Lysate (Adult Normal) [NBP2-09834] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for MAP4K5.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9875_MAP4K5%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-09834-img0001.jpg)