Gene Symbol | MAP4K5 |
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Entrez Gene | 11183 |
Alt Symbol | GCKR, KHS, KHS1, MAPKKKK5 |
Species | Human |
Gene Type | protein-coding |
Description | mitogen-activated protein kinase kinase kinase kinase 5 |
Other Description | MAPK/ERK kinase kinase kinase 5|MEK kinase kinase 5|MEKKK 5|germinal center kinase-related|kinase homologous to SPS1/STE20 |
Swissprots | Q8IYF6 Q9Y4K4 |
Accessions | CAV30709 CAV30710 EAW65710 EAW65711 EAW65712 EAW65713 Q9Y4K4 AK124738 BAG54086 AK313612 BAG36375 BC013159 BC036013 AAH36013 CB959746 CB990293 CN343360 DQ894186 ABM85112 U77129 AAB48435 Z25426 CAA80913 XM_006720013 XP_006720076 XM_011536377 XP_011534679 XM_011536378 XP_011534680 XM_011536379 XP_011534681 XM_011536380 XP_011534682 NM_006575 NP_006566 NM_198794 NP_942089 |
Function | May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. {ECO:0000269|PubMed:9038372}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:9038372}. |
Tissue Specificity | Ubiquitously expressed in all tissues examined, with high levels in the ovary, testis and prostate. {ECO:0000269|PubMed:9038372}. |
KHS CRISPR/Cas9 KO Plasmid (h) - sc-405817 from Santa Cruz Biotechnology
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KHS HDR Plasmid (h) - sc-405817-HDR from Santa Cruz Biotechnology
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KHS Double Nickase Plasmid (h) - sc-405817-NIC from Santa Cruz Biotechnology
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KHS Double Nickase Plasmid (h2) - sc-405817-NIC-2 from Santa Cruz Biotechnology
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KHS CRISPR Activation Plasmid (h) - sc-405817-ACT from Santa Cruz Biotechnology
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KHS CRISPR Activation Plasmid (h2) - sc-405817-ACT-2 from Santa Cruz Biotechnology
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KHS Lentiviral Activation Particles (h) - sc-405817-LAC from Santa Cruz Biotechnology
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KHS Lentiviral Activation Particles (h2) - sc-405817-LAC-2 from Santa Cruz Biotechnology
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KHS siRNA (h) - sc-39245 from Santa Cruz Biotechnology
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KHS shRNA Plasmid (h) - sc-39245-SH from Santa Cruz Biotechnology
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KHS shRNA (h) Lentiviral Particles - sc-39245-V from Santa Cruz Biotechnology
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MAP4K5 RNAi - H00011183-R01V from Novus Biologicals
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MAP4K5 RNAi - H00011183-R04 from Novus Biologicals
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MISSION® esiRNA - EHU120861 from Sigma-Aldrich
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MISSION® siRNA - SIHK1181 from Sigma-Aldrich
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MISSION® siRNA - SIHK1182 from Sigma-Aldrich
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MISSION® siRNA - SIHK1180 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN13002 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13002 from Sigma-Aldrich
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MAP4K5 siRNA (Human) - CRH7663 from Cohesion Biosciences
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MAP4K5 RNAi - H00011183-R03 from Novus Biologicals
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KHS CRISPR/Cas9 KO Plasmid (h2) - sc-405817-KO-2 from Santa Cruz Biotechnology
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KHS HDR Plasmid (h2) - sc-405817-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human MAP4K5 (NM_006575.4) - SHH337847 from Creative biogene
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Human MAP4K5 siRNA - orb268165 from Biorbyt
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