EAF2
| Gene Symbol | EAF2 |
|---|---|
| Entrez Gene | 55840 |
| Alt Symbol | BM040, TRAITS, U19 |
| Species | Human |
| Gene Type | protein-coding |
| Description | ELL associated factor 2 |
| Other Description | ELL-associated factor 2|testosterone-regulated apoptosis inducer and tumor suppressor protein |
| Swissprots | Q9NZ82 Q96CJ1 |
| Accessions | EAW79497 EAW79498 Q96CJ1 AF217516 AAF67627 AF517829 AAO63811 AK301560 BAG63055 AY049020 AAL12223 BC014209 AAH14209 BC014589 BU941228 DQ892648 ABM83574 DQ895887 ABM86813 XM_005247618 XP_005247675 XM_005247620 XP_005247677 XM_011512985 XP_011511287 XM_011512986 XP_011511288 NM_018456 NP_060926 |
| Function | Acts as a transcriptional transactivator of TCEA1 elongation activity (By similarity). Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. Potent inducer of apoptosis in prostatic and non-prostatic cell lines. Inhibits prostate tumor growth in vivo. {ECO:0000250, ECO:0000269|PubMed:12446457, ECO:0000269|PubMed:12907652, ECO:0000269|PubMed:16006523}. |
| Subcellular Location | Nucleus speckle {ECO:0000269|PubMed:12446457, ECO:0000269|PubMed:12907652}. Note=Colocalizes with ELL to nuclear speckles. |
| Tissue Specificity | Expressed in heart, brain, placenta, lung, skeletal muscle, kidney, pancreas, spleen, prostate, testis, small intestine, colon, adrenal, bone marrow, lymph node, spinal gland, stomach, thyroid, trachea, thymus, liver and leukocytes. {ECO:0000269|PubMed:12446457, ECO:0000269|PubMed:12907652}. |
EAF2 293T Cell Transient Overexpression Lysate(Denatured) - H00055840-T01 from Acris Antibodies
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EAF2 overexpression lysate - LY413036 from Acris Antibodies
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EAF2 Overexpression Lysate (Denatured) - H00055840-T01 from Novus Biologicals
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EAF2 Overexpression Lysate (Native) - NBP2-06796 from Novus Biologicals
![Western Blot: EAF2 Overexpression Lysate (Adult Normal) [NBP2-06796] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for EAF2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4799_EAF2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-06796-img0001.jpg)
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Panoply™ Human EAF2 Knockdown Stable Cell Line - CSC-DC004674 from Creative biogene
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