| Gene Symbol |
TAS2R31
|
| Entrez Gene |
259290
|
| Alt Symbol |
T2R31, T2R44, T2R53, TAS2R44
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
taste receptor, type 2, member 31
|
| Other Description |
taste receptor type 2 member 31|taste receptor type 2 member 44|taste receptor type 2 member 53|taste receptor, type 2, member 44
|
| Swissprots |
P59547 P59538 Q645X5 Q17R84
|
| Accessions |
AAM19319 AAM63540 CAI53589 CAI53590 CAV28562 CBJ06463 EAW96226 P59538 BC117421 AAI17422 HQ258369 ADR83123 NM_176885 NP_795366
|
| Function |
Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity). Activated by the sulfonyl amide sweeteners saccharin and acesulfame K. {ECO:0000250}.
|
| Subcellular Location |
Membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.
|
| Top Pathways |
Taste transduction
|