Gene Symbol | TAS2R31 |
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Entrez Gene | 259290 |
Alt Symbol | T2R31, T2R44, T2R53, TAS2R44 |
Species | Human |
Gene Type | protein-coding |
Description | taste receptor, type 2, member 31 |
Other Description | taste receptor type 2 member 31|taste receptor type 2 member 44|taste receptor type 2 member 53|taste receptor, type 2, member 44 |
Swissprots | P59547 P59538 Q645X5 Q17R84 |
Accessions | AAM19319 AAM63540 CAI53589 CAI53590 CAV28562 CBJ06463 EAW96226 P59538 BC117421 AAI17422 HQ258369 ADR83123 NM_176885 NP_795366 |
Function | Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity). Activated by the sulfonyl amide sweeteners saccharin and acesulfame K. {ECO:0000250}. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. |
Top Pathways | Taste transduction |
T2R44 CRISPR/Cas9 KO Plasmid (h) - sc-409081 from Santa Cruz Biotechnology
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T2R44 HDR Plasmid (h) - sc-409081-HDR from Santa Cruz Biotechnology
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T2R44 Double Nickase Plasmid (h) - sc-409081-NIC from Santa Cruz Biotechnology
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T2R44 Double Nickase Plasmid (h2) - sc-409081-NIC-2 from Santa Cruz Biotechnology
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T2R44 CRISPR Activation Plasmid (h) - sc-409081-ACT from Santa Cruz Biotechnology
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T2R44 CRISPR Activation Plasmid (h2) - sc-409081-ACT-2 from Santa Cruz Biotechnology
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T2R44 Lentiviral Activation Particles (h) - sc-409081-LAC from Santa Cruz Biotechnology
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T2R44 Lentiviral Activation Particles (h2) - sc-409081-LAC-2 from Santa Cruz Biotechnology
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T2R44 siRNA (h) - sc-106591 from Santa Cruz Biotechnology
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T2R44 shRNA Plasmid (h) - sc-106591-SH from Santa Cruz Biotechnology
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T2R44 shRNA (h) Lentiviral Particles - sc-106591-V from Santa Cruz Biotechnology
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TAS2R44 RNAi - H00259290-R02 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN21021 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21021 from Sigma-Aldrich
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TAS2R31 siRNA (Human) - CRJ6813 from Cohesion Biosciences
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TAS2R31 - MBS8213069 from MyBioSource
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shRNA set against Human TAS2R31 (NM_176885.2) - SHH423524 from Creative biogene
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shRNA set against Human TAS2R44(NM_176885.2) - SHL057834 from Creative biogene
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Human TAS2R31 siRNA - orb277314 from Biorbyt
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TAS2R31 shRNA Plasmid (Human) - CHJ6813 from Cohesion Biosciences
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TAS2R31 miRNA 3'UTR clone - MiUTR1H-10202 from Creative biogene
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