Gene Symbol | PTPMT1 |
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Entrez Gene | 114971 |
Alt Symbol | DUSP23, MOSP, PLIP, PNAS-129 |
Species | Human |
Gene Type | protein-coding |
Description | protein tyrosine phosphatase, mitochondrial 1 |
Other Description | NB4 apoptosis/differentiation related protein|PTEN-like phosphatase|phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1|phosphoinositide lipid phosphatase|protein-tyrosine phosphatase mitochondrial 1 |
Swissprots | E9PAT8 Q96CR2 Q7Z557 Q9BXV8 Q8WUK0 |
Accessions | EAW67905 Q8WUK0 AF277187 AAK07545 AK294640 BAG57819 AY333987 AAP94732 BC014048 AAH14048 BC018974 BC020242 AAH20242 BC073798 BC107573 BM702054 BM750411 BQ050653 DA476984 DR004030 EU831440 ACE87127 EU831532 ACE86451 HQ447910 ADQ32394 NM_001143984 NP_001137456 NM_175732 NP_783859 |
Function | Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle. Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production. Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues. Probably involved in regulation of insulin secretion in pancreatic beta cells (By similarity). {ECO:0000250}. |
Subcellular Location | Mitochondrion inner membrane {ECO:0000250}. Note=Associated with the inner membrane. {ECO:0000250}. |
Human PTPMT1 full length protein - ab116204 from Abcam
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DUSP23 Antibody Blocking Peptide - LS-E29191 from LifeSpan Bioscience
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DUSP23 Antibody Blocking Peptide - LS-E29192 from LifeSpan Bioscience
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PTPMT1 Antibody Blocking Peptide - LS-E28662 from LifeSpan Bioscience
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PTPMT1 Antibody Blocking Peptide - LS-E28663 from LifeSpan Bioscience
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DUSP23 Recombinant Protein - H00054935-P01 from Novus Biologicals
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PTPMT1 Recombinant Protein - H00114971-P01 from Novus Biologicals
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Recombinant Human DUSP23 Protein - NBP1-72536 from Novus Biologicals
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Recombinant Human PTPMT1 Protein - NBP1-78852 from Novus Biologicals
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Human MOSP protein - orb139548 from Biorbyt
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Human PTPMT1 protein - orb244881 from Biorbyt
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Human DUSP23 protein - orb168255 from Biorbyt
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Human PTPMT1 protein - orb169121 from Biorbyt
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PTPMT1 protein (His tag) - 80R-2095 from Fitzgerald
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PTPMT1 (28-201, His-tag) - AR50178PU-N from Acris Antibodies
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PTPMT1 (28-201, His-tag) - AR50178PU-S from Acris Antibodies
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PTPMT1 - H00114971-P01 from Acris Antibodies
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PTPMT1, 28-201 aa, Human, His tag E.coli - 01-P1353 from ARP American Research Products
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PTPMT1 fusion protein - ag2063 from Proteintech Group
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PTPMT1 Human - ENPS-232 from NeoScientific
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PTPMT1, 28-201 aa , Human, His tag E.coli - GWB-P0685I from Genway Biotech
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Recombinant Human Protein Tyrosine Phosphatase, Mitochondrial 1, His-tagged - PTPMT1-1568H from Creative Biomart
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Recombinant Human PTPMT1, His-tagged - PTPMT1-31117TH from Creative Biomart
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Recombinant Human PTPMT1, His tagged - PTPMT1-2547H from Creative Biomart
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Human PTPMT1 Protein (His Tag) - 12902-H07E-20 from Sino Biological
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