Gene Symbol | IDH2 |
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Entrez Gene | 3418 |
Alt Symbol | D2HGA2, ICD-M, IDH, IDHM, IDP, IDPM, mNADP-IDH |
Species | Human |
Gene Type | protein-coding |
Description | isocitrate dehydrogenase 2 (NADP+), mitochondrial |
Other Description | NADP(+)-specific ICDH|isocitrate dehydrogenase [NADP], mitochondrial|oxalosuccinate decarboxylase |
Swissprots | B4DFL2 B2R6L6 P48735 Q96GT3 |
Accessions | CBN62262 CBN63691 EAX02082 EAX02083 P48735 AK222916 BAD96636 AK294148 BAG57473 AK299987 BAG61808 AK312627 BAG35513 AK316388 BAH14759 BC009244 AAH09244 BC071828 AAH71828 DQ892817 ABM83743 DQ896063 ABM87062 HY010337 X69433 CAA49208 NM_001289910 NP_001276839 NM_001290114 NP_001277043 NM_002168 NP_002159 |
Function | Plays a role in intermediary metabolism and energy production. It may tightly associate or interact with the pyruvate dehydrogenase complex. |
Subcellular Location | Mitochondrion. |
Top Pathways | Citrate cycle (TCA cycle), Peroxisome, Glutathione metabolism, Biosynthesis of amino acids, 2-Oxocarboxylic acid metabolism |
IDH2 CRISPR/Cas9 KO Plasmid (h) - sc-401417 from Santa Cruz Biotechnology
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IDH2 HDR Plasmid (h) - sc-401417-HDR from Santa Cruz Biotechnology
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IDH2 Double Nickase Plasmid (h) - sc-401417-NIC from Santa Cruz Biotechnology
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IDH2 Double Nickase Plasmid (h2) - sc-401417-NIC-2 from Santa Cruz Biotechnology
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IDH2 CRISPR Activation Plasmid (h) - sc-401417-ACT from Santa Cruz Biotechnology
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IDH2 CRISPR Activation Plasmid (h2) - sc-401417-ACT-2 from Santa Cruz Biotechnology
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IDH2 Lentiviral Activation Particles (h) - sc-401417-LAC from Santa Cruz Biotechnology
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IDH2 Lentiviral Activation Particles (h2) - sc-401417-LAC-2 from Santa Cruz Biotechnology
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IDH2 siRNA (h) - sc-62487 from Santa Cruz Biotechnology
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IDH2 shRNA Plasmid (h) - sc-62487-SH from Santa Cruz Biotechnology
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IDH2 shRNA (h) Lentiviral Particles - sc-62487-V from Santa Cruz Biotechnology
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IDH2 RNAi - H00003418-R01 from Novus Biologicals
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MISSION® esiRNA - EHU004281 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2058 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2058 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01769 from Sigma-Aldrich
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IDH2 siRNA (Human) - CRH2313 from Cohesion Biosciences
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IDH2 - MBS8207506 from MyBioSource
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shRNA set against Human IDH2 (NM_002168.2) - SHH316569 from Creative biogene
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Human IDH2 siRNA - orb262815 from Biorbyt
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IDH2 shRNA Plasmid (Human) - CHH2313 from Cohesion Biosciences
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IDH2 miRNA 3'UTR clone - MiUTR1H-04788 from Creative biogene
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