| Gene Symbol |
SNX10
|
| Entrez Gene |
29887
|
| Alt Symbol |
OPTB8
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
sorting nexin 10
|
| Other Description |
sorting nexin-10
|
| Swissprots |
Q8IYT5 E9PFH5 Q9Y5X0
|
| Accessions |
AAS02029 AAS07476 EAL24234 EAW93848 EAW93849 EAW93850 EAW93851 Q9Y5X0 AF121860 AAD27833 AK296142 BAG58882 AK307905 AK309162 AK311256 AK312850 BAG35703 AK316088 BAH14459 BC031050 AAH31050 BC034992 AAH34992 BG399132 BJ995940 BM147840 BM147978 BX648363 DQ892420 ABM83346 DQ895634 ABM86560 XM_006715710 XP_006715773 XM_006715711 XP_006715774 XM_006715712 XP_006715775 NM_001199835 NP_001186764 NM_001199837 NP_001186766 NM_001199838 NP_001186767 NM_013322 NP_037454 NR_037670
|
| Function |
Probable phosphoinositide-binding protein involved in protein sorting and membrane trafficking in endosomes. Plays a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium. Required for the localization to the cilium of V-ATPase subunit ATP6V1D and ATP6V0D1, and RAB8A. Involved in osteoclast differentiation and therefore bone resorption. {ECO:0000269|PubMed:17012226, ECO:0000269|PubMed:21844891, ECO:0000269|PubMed:22499339}.
|
| Subcellular Location |
Cytoplasm. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=May also localize to nucleus and endoplasmic reticulum.
|