| Gene Symbol |
Polr1c
|
| Entrez Gene |
20016
|
| Alt Symbol |
40kDa, AA409007, AA959927, AL024089, Polr1e, RPA40, Rpo1-1
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
polymerase (RNA) I polypeptide C
|
| Other Description |
AC40|DNA-directed RNA polymerase I subunit C|DNA-directed RNA polymerases I and III 40 kDa polypeptide|DNA-directed RNA polymerases I and III subunit RPAC1|RNA polymerase 1-1 (40 kDa subunit)|RNA polymerases I and III subunit AC1|RPC40
|
| Swissprots |
Q3UJZ9 P52432
|
| Accessions |
EDL23483 EDL23484 P52432 AK132114 BAE20986 AK146240 BAE27005 AK180462 BC130018 AAI30019 BY267923 CJ207889 NM_009085 NP_033111
|
| Function |
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively. RPAC1 is part of the Pol core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000250}.
|
| Top Pathways |
Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, Purine metabolism, RNA polymerase, Pyrimidine metabolism
|