| Gene Symbol |
TXNDC11
|
| Entrez Gene |
51061
|
| Alt Symbol |
EFP1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
thioredoxin domain containing 11
|
| Other Description |
EF-hand binding protein 1|EF-hand-binding protein 1|thioredoxin domain-containing protein 11
|
| Swissprots |
Q6PJA6 O95887 Q96K53 Q8N2Q4 Q96K45 Q6PKC3
|
| Accessions |
EAW85142 EAW85143 EAW85144 EAW85145 Q6PKC3 AF131780 AAD20043 AK027464 BAB55129 AK027646 BAB55262 AK074534 BAC11044 AK297094 BAG59607 BC002856 AAH02856 BC013727 AAH13727 BC018635 AAH18635 BX648407 CN347909 CR457152 CAG33433 XM_005255346 XP_005255403 XM_011522515 XP_011520817 XM_011522516 XP_011520818 NM_001303447 NP_001290376 NM_015914 NP_056998
|
| Function |
May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Widely expressed at low level. Expressed at higher level in thyroid and prostate. {ECO:0000269|PubMed:15561711}.
|