Gene Symbol | TXNDC11 |
---|---|
Entrez Gene | 51061 |
Alt Symbol | EFP1 |
Species | Human |
Gene Type | protein-coding |
Description | thioredoxin domain containing 11 |
Other Description | EF-hand binding protein 1|EF-hand-binding protein 1|thioredoxin domain-containing protein 11 |
Swissprots | Q6PJA6 O95887 Q96K53 Q8N2Q4 Q96K45 Q6PKC3 |
Accessions | EAW85142 EAW85143 EAW85144 EAW85145 Q6PKC3 AF131780 AAD20043 AK027464 BAB55129 AK027646 BAB55262 AK074534 BAC11044 AK297094 BAG59607 BC002856 AAH02856 BC013727 AAH13727 BC018635 AAH18635 BX648407 CN347909 CR457152 CAG33433 XM_005255346 XP_005255403 XM_011522515 XP_011520817 XM_011522516 XP_011520818 NM_001303447 NP_001290376 NM_015914 NP_056998 |
Function | May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
Tissue Specificity | Widely expressed at low level. Expressed at higher level in thyroid and prostate. {ECO:0000269|PubMed:15561711}. |
EFP1 CRISPR/Cas9 KO Plasmid (h) - sc-412101 from Santa Cruz Biotechnology
|
||||||||
EFP1 HDR Plasmid (h) - sc-412101-HDR from Santa Cruz Biotechnology
|
||||||||
EFP1 Double Nickase Plasmid (h) - sc-412101-NIC from Santa Cruz Biotechnology
|
||||||||
EFP1 Double Nickase Plasmid (h2) - sc-412101-NIC-2 from Santa Cruz Biotechnology
|
||||||||
EFP1 CRISPR Activation Plasmid (h) - sc-412101-ACT from Santa Cruz Biotechnology
|
||||||||
EFP1 CRISPR Activation Plasmid (h2) - sc-412101-ACT-2 from Santa Cruz Biotechnology
|
||||||||
EFP1 Lentiviral Activation Particles (h) - sc-412101-LAC from Santa Cruz Biotechnology
|
||||||||
EFP1 Lentiviral Activation Particles (h2) - sc-412101-LAC-2 from Santa Cruz Biotechnology
|
||||||||
EFP1 siRNA (h) - sc-93003 from Santa Cruz Biotechnology
|
||||||||
EFP1 shRNA Plasmid (h) - sc-93003-SH from Santa Cruz Biotechnology
|
||||||||
EFP1 shRNA (h) Lentiviral Particles - sc-93003-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU091351 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN22302 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22302 from Sigma-Aldrich
|
||||||||
TXNDC11 siRNA (Human) - CRH9485 from Cohesion Biosciences
|
||||||||
TXNDC11 - MBS827838 from MyBioSource
|
||||||||
shRNA set against Human TXNDC11 (NM_015914.5) - SHH438200 from Creative biogene
|
||||||||
shRNA set against Human TXNDC11(NM_015914.5) - SHL107910 from Creative biogene
|
||||||||
Human TXNDC11 siRNA - orb269987 from Biorbyt
|
||||||||
TXNDC11 shRNA Plasmid (Human) - CHH9485 from Cohesion Biosciences
|
||||||||
TXNDC11 miRNA 3'UTR clone - MiUTR1H-10896 from Creative biogene
|