| Gene Symbol |
LIPN
|
| Entrez Gene |
643418
|
| Alt Symbol |
ARCI8, LI4, LIPL4, bA186O14.3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
lipase, family member N
|
| Other Description |
lipase member N|lipase-like abhydrolase domain-containing protein 4
|
| Swissprots |
A7KIH9 Q5VXI9
|
| Accessions |
Q5VXI9 EF426483 ABR08388 XM_005270049 XP_005270106 XM_011540083 XP_011538385 XM_011540084 XP_011538386 XM_011540085 XP_011538387 XM_011540086 XP_011538388 XR_945801 NM_001102469 NP_001095939
|
| Function |
Plays a highly specific role in the last step of keratinocyte differentiation. May have an essential function in lipid metabolism of the most differentiated epidermal layers. {ECO:0000269|PubMed:17562024}.
|
| Subcellular Location |
Secreted {ECO:0000305}.
|
| Tissue Specificity |
Highly expressed in the epidermis in the granular keratinocytes. Also detected in other tissues, although at much lower levels, including lung and spleen. {ECO:0000269|PubMed:17562024, ECO:0000269|PubMed:21439540}.
|
![Western Blot: LIPN Overexpression Lysate (Adult Normal) [NBP2-08240] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for LIPN.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/10235_LIPN%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-08240-img0001.jpg)