| Gene Symbol |
Cdkn2b
|
| Entrez Gene |
12579
|
| Alt Symbol |
AV083695, INK4b, MTS2, p15, p15(INK4b), p15INK4b
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
|
| Other Description |
cyclin-dependent kinase 4 inhibitor B|cyclin-dependent kinase inhibitor p15|cyclin-dependent kinase inhibitor p15INK4b|cyclin-dependent kinase inhibitor protein|p14-INK4b|p15-INK4b
|
| Swissprots |
P55271
|
| Accessions |
AAB39833 AAB94534 AAD00232 AAD00233 AAD00234 AAD00356 AAD00357 AAD00358 EDL30950 P55271 AF059567 AAC14569 AK144132 BAE25719 AK146668 BC002010 AAH02010 DT919921 NM_007670 NP_031696
|
| Function |
Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest (By similarity). {ECO:0000250}.
|
| Tissue Specificity |
Expressed ubiquitously.
|
| Top Pathways |
Cell cycle, TGF-beta signaling pathway, Small cell lung cancer, HTLV-I infection, Viral carcinogenesis
|