Gene Symbol |
PEX3
|
Entrez Gene |
8504
|
Alt Symbol |
PBD10A, TRG18
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
peroxisomal biogenesis factor 3
|
Other Description |
peroxin-3|peroxisomal assembly protein PEX3|transformation-related protein 18
|
Swissprots |
Q6FGP5 P56589
|
Accessions |
CAA08904 EAW47866 P56589 AB035307 BAA97993 AJ001625 CAA04879 AJ131389 CAA10362 AK023593 AK025644 AK300907 BAG62543 AU137342 AY277600 AAQ18039 BC014551 AAH14551 BC015506 AAH15506 BP377713 BX648803 CR542062 CAG46859 DB576209 NM_003630 NP_003621
|
Function |
Involved in peroxisome biosynthesis and integrity. Assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, is necessary for the import of peroxisomal membrane proteins in the peroxisomes. {ECO:0000269|PubMed:10848631, ECO:0000269|PubMed:15007061}.
|
Subcellular Location |
Peroxisome membrane {ECO:0000269|PubMed:11390669}; Multi-pass membrane protein {ECO:0000269|PubMed:11390669}.
|
Tissue Specificity |
Found in all examined tissues.
|
Top Pathways |
Peroxisome
|