Gene Symbol | PEX3 |
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Entrez Gene | 8504 |
Alt Symbol | PBD10A, TRG18 |
Species | Human |
Gene Type | protein-coding |
Description | peroxisomal biogenesis factor 3 |
Other Description | peroxin-3|peroxisomal assembly protein PEX3|transformation-related protein 18 |
Swissprots | Q6FGP5 P56589 |
Accessions | CAA08904 EAW47866 P56589 AB035307 BAA97993 AJ001625 CAA04879 AJ131389 CAA10362 AK023593 AK025644 AK300907 BAG62543 AU137342 AY277600 AAQ18039 BC014551 AAH14551 BC015506 AAH15506 BP377713 BX648803 CR542062 CAG46859 DB576209 NM_003630 NP_003621 |
Function | Involved in peroxisome biosynthesis and integrity. Assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, is necessary for the import of peroxisomal membrane proteins in the peroxisomes. {ECO:0000269|PubMed:10848631, ECO:0000269|PubMed:15007061}. |
Subcellular Location | Peroxisome membrane {ECO:0000269|PubMed:11390669}; Multi-pass membrane protein {ECO:0000269|PubMed:11390669}. |
Tissue Specificity | Found in all examined tissues. |
Top Pathways | Peroxisome |
Peroxin 3 CRISPR/Cas9 KO Plasmid (h) - sc-405639 from Santa Cruz Biotechnology
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Peroxin 3 HDR Plasmid (h) - sc-405639-HDR from Santa Cruz Biotechnology
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Peroxin 3 Double Nickase Plasmid (h) - sc-405639-NIC from Santa Cruz Biotechnology
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Peroxin 3 Double Nickase Plasmid (h2) - sc-405639-NIC-2 from Santa Cruz Biotechnology
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Peroxin 3 CRISPR Activation Plasmid (h) - sc-405639-ACT from Santa Cruz Biotechnology
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Peroxin 3 CRISPR Activation Plasmid (h2) - sc-405639-ACT-2 from Santa Cruz Biotechnology
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Peroxin 3 Lentiviral Activation Particles (h) - sc-405639-LAC from Santa Cruz Biotechnology
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Peroxin 3 Lentiviral Activation Particles (h2) - sc-405639-LAC-2 from Santa Cruz Biotechnology
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Peroxin 3 siRNA (h) - sc-95091 from Santa Cruz Biotechnology
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Peroxin 3 shRNA Plasmid (h) - sc-95091-SH from Santa Cruz Biotechnology
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Peroxin 3 shRNA (h) Lentiviral Particles - sc-95091-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU067571 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16641 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16641 from Sigma-Aldrich
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PEX3 siRNA (Human) - CRH5578 from Cohesion Biosciences
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shRNA set against Human PEX3 (NM_003630.2) - SHH373768 from Creative biogene
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Human PEX3 siRNA - orb266080 from Biorbyt
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PEX3 shRNA Plasmid (Human) - CHH5578 from Cohesion Biosciences
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PEX3 miRNA 3'UTR clone - MiUTR3H-05731 from Creative biogene
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