Gene Symbol |
NDUFB11
|
Entrez Gene |
54539
|
Alt Symbol |
CI-ESSS, ESSS, NP17.3, Np15, P17.3
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa
|
Other Description |
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial|NADH-ubiquinone oxidoreductase ESSS subunit|complex I NP17.3 subunit|complex I-ESSS|neuronal protein 17.3
|
Swissprots |
Q6IAB6 Q5JRR3 Q9NX14 Q8WZ96 Q5JRR4 Q9BXX9
|
Accessions |
CAM55978 EAW59281 EAW59282 Q9NX14 AA287166 AF044213 AAL32064 AF134476 AAP97253 AF251063 AAK34953 AK000501 BAA91208 AY359056 AAQ89415 BC010665 AAH10665 BC107805 AAI07806 BU682304 CR457239 CAG33520 NM_001135998 NP_001129470 NM_019056 NP_061929
|
Function |
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
|
Subcellular Location |
Mitochondrion inner membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
|
Tissue Specificity |
Ubiquitous.
|
Top Pathways |
Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation
|