Gene Symbol | NDUFB11 |
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Entrez Gene | 54539 |
Alt Symbol | CI-ESSS, ESSS, NP17.3, Np15, P17.3 |
Species | Human |
Gene Type | protein-coding |
Description | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa |
Other Description | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial|NADH-ubiquinone oxidoreductase ESSS subunit|complex I NP17.3 subunit|complex I-ESSS|neuronal protein 17.3 |
Swissprots | Q6IAB6 Q5JRR3 Q9NX14 Q8WZ96 Q5JRR4 Q9BXX9 |
Accessions | CAM55978 EAW59281 EAW59282 Q9NX14 AA287166 AF044213 AAL32064 AF134476 AAP97253 AF251063 AAK34953 AK000501 BAA91208 AY359056 AAQ89415 BC010665 AAH10665 BC107805 AAI07806 BU682304 CR457239 CAG33520 NM_001135998 NP_001129470 NM_019056 NP_061929 |
Function | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
Subcellular Location | Mitochondrion inner membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
Tissue Specificity | Ubiquitous. |
Top Pathways | Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
NDUFB11 CRISPR/Cas9 KO Plasmid (h) - sc-407078 from Santa Cruz Biotechnology
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NDUFB11 HDR Plasmid (h) - sc-407078-HDR from Santa Cruz Biotechnology
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NDUFB11 Double Nickase Plasmid (h) - sc-407078-NIC from Santa Cruz Biotechnology
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NDUFB11 Double Nickase Plasmid (h2) - sc-407078-NIC-2 from Santa Cruz Biotechnology
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NDUFB11 CRISPR Activation Plasmid (h) - sc-407078-ACT from Santa Cruz Biotechnology
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NDUFB11 CRISPR Activation Plasmid (h2) - sc-407078-ACT-2 from Santa Cruz Biotechnology
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NDUFB11 Lentiviral Activation Particles (h) - sc-407078-LAC from Santa Cruz Biotechnology
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NDUFB11 Lentiviral Activation Particles (h2) - sc-407078-LAC-2 from Santa Cruz Biotechnology
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NDUFB11 siRNA (h) - sc-90885 from Santa Cruz Biotechnology
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NDUFB11 shRNA Plasmid (h) - sc-90885-SH from Santa Cruz Biotechnology
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NDUFB11 shRNA (h) Lentiviral Particles - sc-90885-V from Santa Cruz Biotechnology
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NDUFB11 RNAi - H00054539-R01 from Novus Biologicals
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MISSION® esiRNA - EHU064101 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15155 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15155 from Sigma-Aldrich
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NDUFB11 siRNA (Human) - CRJ0122 from Cohesion Biosciences
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shRNA set against Human NDUFB11 (NM_019056.6) - SHH350708 from Creative biogene
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Human NDUFB11 siRNA - orb270623 from Biorbyt
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NDUFB11 shRNA Plasmid (Human) - CHJ0122 from Cohesion Biosciences
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NDUFB11 miRNA 3'UTR clone - MiUTR3H-02742 from Creative biogene
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NDUFB11 miRNA 3'UTR clone - MiUTR3H-02743 from Creative biogene
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