| Gene Symbol |
PCGF5
|
| Entrez Gene |
84333
|
| Alt Symbol |
RNF159
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
polycomb group ring finger 5
|
| Other Description |
RING finger protein 159|polycomb group RING finger protein 5|ring finger protein (C3HC4 type) 159
|
| Swissprots |
Q86SE9 Q6PK47 B7Z892 Q86TD0 D3DR33
|
| Accessions |
EAW50112 EAW50113 EAW50114 Q86SE9 AK055625 AK303014 BAH13878 AL832003 CAD89905 AL832496 CAD91165 AM393626 CAL38502 BC007377 AAH07377 BC044910 BC051845 AAH51845 BI464238 BQ420347 BY994354 CB266840 XM_006718030 XP_006718093 XM_011540271 XP_011538573 XM_011540272 XP_011538574 NM_001256549 NP_001243478 NM_001257101 NP_001244030 NM_032373 NP_115749 NR_046310 NR_046435
|
| Function |
Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:21282530}.
|
| Top Pathways |
Signaling pathways regulating pluripotency of stem cells
|