Gene Symbol | PCGF5 |
---|---|
Entrez Gene | 84333 |
Alt Symbol | RNF159 |
Species | Human |
Gene Type | protein-coding |
Description | polycomb group ring finger 5 |
Other Description | RING finger protein 159|polycomb group RING finger protein 5|ring finger protein (C3HC4 type) 159 |
Swissprots | Q86SE9 Q6PK47 B7Z892 Q86TD0 D3DR33 |
Accessions | EAW50112 EAW50113 EAW50114 Q86SE9 AK055625 AK303014 BAH13878 AL832003 CAD89905 AL832496 CAD91165 AM393626 CAL38502 BC007377 AAH07377 BC044910 BC051845 AAH51845 BI464238 BQ420347 BY994354 CB266840 XM_006718030 XP_006718093 XM_011540271 XP_011538573 XM_011540272 XP_011538574 NM_001256549 NP_001243478 NM_001257101 NP_001244030 NM_032373 NP_115749 NR_046310 NR_046435 |
Function | Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:21282530}. |
Top Pathways | Signaling pathways regulating pluripotency of stem cells |
PCGF5 CRISPR/Cas9 KO Plasmid (h) - sc-416432 from Santa Cruz Biotechnology
|
||||||||
PCGF5 HDR Plasmid (h) - sc-416432-HDR from Santa Cruz Biotechnology
|
||||||||
PCGF5 Double Nickase Plasmid (h) - sc-416432-NIC from Santa Cruz Biotechnology
|
||||||||
PCGF5 Double Nickase Plasmid (h2) - sc-416432-NIC-2 from Santa Cruz Biotechnology
|
||||||||
PCGF5 CRISPR Activation Plasmid (h) - sc-416432-ACT from Santa Cruz Biotechnology
|
||||||||
PCGF5 CRISPR Activation Plasmid (h2) - sc-416432-ACT-2 from Santa Cruz Biotechnology
|
||||||||
PCGF5 Lentiviral Activation Particles (h) - sc-416432-LAC from Santa Cruz Biotechnology
|
||||||||
PCGF5 Lentiviral Activation Particles (h2) - sc-416432-LAC-2 from Santa Cruz Biotechnology
|
||||||||
PCGF5 siRNA (h) - sc-90356 from Santa Cruz Biotechnology
|
||||||||
PCGF5 shRNA Plasmid (h) - sc-90356-SH from Santa Cruz Biotechnology
|
||||||||
PCGF5 shRNA (h) Lentiviral Particles - sc-90356-V from Santa Cruz Biotechnology
|
||||||||
PCGF5 RNAi - H00084333-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU069571 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN16474 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16474 from Sigma-Aldrich
|
||||||||
PCGF5 siRNA (Human) - CRJ3452 from Cohesion Biosciences
|
||||||||
shRNA set against Human PCGF5 (NM_032373.4) - SHH371832 from Creative biogene
|
||||||||
PCGF5 shRNA Plasmid (Human) - CHJ3452 from Cohesion Biosciences
|
||||||||