| Gene Symbol |
SEL1L
|
| Entrez Gene |
6400
|
| Alt Symbol |
PRO1063, SEL1-LIKE, SEL1L1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
sel-1 suppressor of lin-12-like (C. elegans)
|
| Other Description |
Suppressor of lin 12 (sel-1), C. elegans, homolog of|protein sel-1 homolog 1|sel-1 suppressor of lin-12-like 1|suppressor of lin-12-like protein 1
|
| Swissprots |
Q9UBV2 Q6UWT6 Q9UHK7 Q9P1T9
|
| Accessions |
AAF24176 AAL40905 BAA89204 CCQ43296 EAW81344 Q9UBV2 AB020335 BAA87904 AF052059 AAF29413 AK075511 AY358651 AAQ89014 BC040498 AAH40498 BC054336 BC172282 AAI72282 BC172577 AAI72577 BP358857 CA447094 CB986742 DA351814 DA833312 ES313707 U11037 AAB52516 XM_005267988 XP_005268045 XM_005267989 XP_005268046 NM_001244984 NP_001231913 NM_005065 NP_005056
|
| Function |
May play a role in Notch signaling (By similarity). May be involved in the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. {ECO:0000250, ECO:0000269|PubMed:16186509}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000269|PubMed:16186509}; Single-pass type I membrane protein {ECO:0000269|PubMed:16186509}.
|
| Tissue Specificity |
Highly expressed in pancreas.
|
| Top Pathways |
Protein processing in endoplasmic reticulum
|