Gene Symbol | SEL1L |
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Entrez Gene | 6400 |
Alt Symbol | PRO1063, SEL1-LIKE, SEL1L1 |
Species | Human |
Gene Type | protein-coding |
Description | sel-1 suppressor of lin-12-like (C. elegans) |
Other Description | Suppressor of lin 12 (sel-1), C. elegans, homolog of|protein sel-1 homolog 1|sel-1 suppressor of lin-12-like 1|suppressor of lin-12-like protein 1 |
Swissprots | Q9UBV2 Q6UWT6 Q9UHK7 Q9P1T9 |
Accessions | AAF24176 AAL40905 BAA89204 CCQ43296 EAW81344 Q9UBV2 AB020335 BAA87904 AF052059 AAF29413 AK075511 AY358651 AAQ89014 BC040498 AAH40498 BC054336 BC172282 AAI72282 BC172577 AAI72577 BP358857 CA447094 CB986742 DA351814 DA833312 ES313707 U11037 AAB52516 XM_005267988 XP_005268045 XM_005267989 XP_005268046 NM_001244984 NP_001231913 NM_005065 NP_005056 |
Function | May play a role in Notch signaling (By similarity). May be involved in the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. {ECO:0000250, ECO:0000269|PubMed:16186509}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:16186509}; Single-pass type I membrane protein {ECO:0000269|PubMed:16186509}. |
Tissue Specificity | Highly expressed in pancreas. |
Top Pathways | Protein processing in endoplasmic reticulum |
Sel-1L CRISPR/Cas9 KO Plasmid (h) - sc-403861 from Santa Cruz Biotechnology
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Sel-1L HDR Plasmid (h) - sc-403861-HDR from Santa Cruz Biotechnology
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Sel-1L Double Nickase Plasmid (h) - sc-403861-NIC from Santa Cruz Biotechnology
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Sel-1L Double Nickase Plasmid (h2) - sc-403861-NIC-2 from Santa Cruz Biotechnology
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Sel-1L CRISPR Activation Plasmid (h) - sc-403861-ACT from Santa Cruz Biotechnology
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Sel-1L CRISPR Activation Plasmid (h2) - sc-403861-ACT-2 from Santa Cruz Biotechnology
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Sel-1L Lentiviral Activation Particles (h) - sc-403861-LAC from Santa Cruz Biotechnology
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Sel-1L Lentiviral Activation Particles (h2) - sc-403861-LAC-2 from Santa Cruz Biotechnology
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Sel-1L siRNA (h) - sc-61514 from Santa Cruz Biotechnology
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Sel-1L shRNA Plasmid (h) - sc-61514-SH from Santa Cruz Biotechnology
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Sel-1L shRNA (h) Lentiviral Particles - sc-61514-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU068911 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19049 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19049 from Sigma-Aldrich
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SEL1L siRNA (Human) - CRH4323 from Cohesion Biosciences
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SEL1L - MBS8228732 from MyBioSource
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shRNA set against Human Sel1l (NM_005065.5) - SHH404016 from Creative biogene
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Human SEL1L siRNA - orb264825 from Biorbyt
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SEL1L shRNA Plasmid (Human) - CHH4323 from Cohesion Biosciences
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