Gene Symbol | EAPP |
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Entrez Gene | 55837 |
Alt Symbol | BM036, C14orf11 |
Species | Human |
Gene Type | protein-coding |
Description | E2F-associated phosphoprotein |
Other Description | - |
Swissprots | Q9BVF4 Q9NZ86 Q56P03 Q9NWV5 |
Accessions | CCQ43598 EAW65920 EAW65921 EAW65922 Q56P03 AF217512 AAF67623 AK000585 BAA91271 AK225467 AK225477 AK225991 AY157300 AAO17041 AY157301 AAO17042 AY869694 AAX63200 BC001245 AAH01245 CD702290 HQ447367 ADQ31853 XM_011536958 XP_011535260 XM_011536959 XP_011535261 NM_018453 NP_060923 |
Function | May play an important role in the fine-tuning of both major E2F1 activities, the regulation of the cell-cycle and the induction of apoptosis. Promotes S-phase entry, and inhibits p14(ARP) expression. {ECO:0000269|PubMed:15716352}. |
Subcellular Location | Cytoplasm. Nucleus. |
Tissue Specificity | Ubiquitously expressed. Highest levels in heart, placenta, skeletal muscle and pancreas. Lower levels in brain, lung and kidney. In the brain, expressed in all regions with high levels in the cerebellum and cerebral cortex. Expressed in COS1 and transformed skin fibroblasts. {ECO:0000269|PubMed:15716352, ECO:0000269|PubMed:15820313}. |
EAPP (1E4) Mouse mAb - 5166 from Cell Signaling Technology
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EAPP (C-9) - sc-365756 from Santa Cruz Biotechnology
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EAPP (FL-285) - sc-135138 from Santa Cruz Biotechnology
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EAPP (1E4) - sc-130357 from Santa Cruz Biotechnology
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Anti-EAPP antibody - ab128697 from Abcam
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Anti-EAPP antibody - ab121154 from Abcam
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Anti-EAPP antibody [1E4] - ab169860 from Abcam
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Anti-EAPP antibody - C-terminal - ab171610 from Abcam
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Anti-EAPP antibody - N-terminal - ab167466 from Abcam
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Anti-EAPP Antibody (aa203-233, AP) - LS-C208848 from LifeSpan Bioscience
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Anti-EAPP Antibody (aa203-233, APC) - LS-C208849 from LifeSpan Bioscience
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Anti-EAPP Antibody (aa203-233, FITC) - LS-C208852 from LifeSpan Bioscience
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Anti-EAPP Antibody (aa203-233, Biotin) - LS-C208850 from LifeSpan Bioscience
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Anti-EAPP Antibody (aa203-233, Azide-free, HRP) - LS-C208853 from LifeSpan Bioscience
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Anti-EAPP Antibody (aa203-233, PE) - LS-C208855 from LifeSpan Bioscience
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Anti-EAPP Antibody (aa203-233) - LS-C329484 from LifeSpan Bioscience
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Anti-EAPP Antibody (N-Terminus) - LS-C345900 from LifeSpan Bioscience
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Anti-EAPP Antibody (aa204-233) - LS-C167603 from LifeSpan Bioscience
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Anti-EAPP Antibody (aa7-192) - LS-C179020 from LifeSpan Bioscience
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EAPP Antibody - NBP1-88579 from Novus Biologicals
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ANTI-EAPP(C-TERMINAL) antibody produced in rabbit - SAB1307029 from Sigma-Aldrich
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Anti-EAPP antibody produced in rabbit - HPA002916 from Sigma-Aldrich
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EAPP-Antibody-C-term - AP12971b from Abgent, a WuXi AppTec company
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EAPP antibody [N2C3] - GTX106827 from GeneTex
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EAPP Antibody - C-terminal region (OAAB09257) - OAAB09257 from Aviva Systems Biology
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