| Gene Symbol |
ZHX1
|
| Entrez Gene |
11244
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
zinc fingers and homeoboxes 1
|
| Other Description |
zinc finger and homeodomain protein 1|zinc fingers and homeobox 1|zinc fingers and homeoboxes protein 1
|
| Swissprots |
Q8IWD8 Q9UKY1
|
| Accessions |
EAW92027 EAW92028 EAW92029 Q9UKY1 AF106862 AAD50624 AF195766 AAF35183 AK025236 AK094451 AK289532 BAF82221 BC040481 AAH40481 BQ008088 CA776642 CN352595 DA238313 NM_001017926 NP_001017926 NM_007222 NP_009153 NR_037873 NR_037874
|
| Function |
Acts as a transcriptional repressor. Increases DNMT3B- mediated repressive transcriptional activity when DNMT3B is tethered to DNA. May link molecule between DNMT3B and other co- repressor proteins. {ECO:0000269|PubMed:12237128}.
|
| Subcellular Location |
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000269|PubMed:12237128, ECO:0000269|PubMed:17056598}. Note=Colocalized in the nucleus with DNMT3B.
|
| Tissue Specificity |
Ubiquitously expressed. Expressed in podocytes. {ECO:0000269|PubMed:10441475, ECO:0000269|PubMed:17056598}.
|
![Western Blot: ZHX1 Overexpression Lysate (Adult Normal) [NBP2-07518] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ZHX1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5755_ZHX1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-07518-img0001.jpg)