Gene Symbol | ZHX1 |
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Entrez Gene | 11244 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | zinc fingers and homeoboxes 1 |
Other Description | zinc finger and homeodomain protein 1|zinc fingers and homeobox 1|zinc fingers and homeoboxes protein 1 |
Swissprots | Q8IWD8 Q9UKY1 |
Accessions | EAW92027 EAW92028 EAW92029 Q9UKY1 AF106862 AAD50624 AF195766 AAF35183 AK025236 AK094451 AK289532 BAF82221 BC040481 AAH40481 BQ008088 CA776642 CN352595 DA238313 NM_001017926 NP_001017926 NM_007222 NP_009153 NR_037873 NR_037874 |
Function | Acts as a transcriptional repressor. Increases DNMT3B- mediated repressive transcriptional activity when DNMT3B is tethered to DNA. May link molecule between DNMT3B and other co- repressor proteins. {ECO:0000269|PubMed:12237128}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000269|PubMed:12237128, ECO:0000269|PubMed:17056598}. Note=Colocalized in the nucleus with DNMT3B. |
Tissue Specificity | Ubiquitously expressed. Expressed in podocytes. {ECO:0000269|PubMed:10441475, ECO:0000269|PubMed:17056598}. |
ZHX1 CRISPR/Cas9 KO Plasmid (h) - sc-407666 from Santa Cruz Biotechnology
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ZHX1 HDR Plasmid (h) - sc-407666-HDR from Santa Cruz Biotechnology
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ZHX1 Double Nickase Plasmid (h) - sc-407666-NIC from Santa Cruz Biotechnology
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ZHX1 Double Nickase Plasmid (h2) - sc-407666-NIC-2 from Santa Cruz Biotechnology
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ZHX1 CRISPR Activation Plasmid (h) - sc-407666-ACT from Santa Cruz Biotechnology
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ZHX1 CRISPR Activation Plasmid (h2) - sc-407666-ACT-2 from Santa Cruz Biotechnology
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ZHX1 Lentiviral Activation Particles (h) - sc-407666-LAC from Santa Cruz Biotechnology
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ZHX1 Lentiviral Activation Particles (h2) - sc-407666-LAC-2 from Santa Cruz Biotechnology
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ZHX1 siRNA (h) - sc-61827 from Santa Cruz Biotechnology
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ZHX1 shRNA Plasmid (h) - sc-61827-SH from Santa Cruz Biotechnology
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ZHX1 shRNA (h) Lentiviral Particles - sc-61827-V from Santa Cruz Biotechnology
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ZHX1 RNAi - H00011244-R01 from Novus Biologicals
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MISSION® esiRNA - EHU049181 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN23215 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23215 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12825 from Sigma-Aldrich
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ZHX1 siRNA (Human) - CRH7706 from Cohesion Biosciences
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ZHX1 RNAi - H00011244-R02 from Novus Biologicals
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ZHX1 - MBS828148 from MyBioSource
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shRNA set against Human ZHX1 (NM_007222.4) - SHH452588 from Creative biogene
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ZHX1 shRNA Plasmid (Human) - CHH7706 from Cohesion Biosciences
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ZHX1 miRNA 3'UTR clone - MiUTR3H-07073 from Creative biogene
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ZHX1 miRNA 3'UTR clone - MiUTR3H-07074 from Creative biogene
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