| Gene Symbol |
Htr1f
|
| Entrez Gene |
15557
|
| Alt Symbol |
Htr1eb
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
5-hydroxytryptamine (serotonin) receptor 1F
|
| Other Description |
5-HT-1E-beta|5-HT-1F|5-HT1F|5-hydroxytryptamine (serotonin) receptor 1E beta|5-hydroxytryptamine receptor 1F|serotonin receptor 1F
|
| Swissprots |
Q02284
|
| Accessions |
EDK98243 Q02284 AK045364 BAC32328 BC120507 AAI20508 BC137604 AAI37605 Z14224 CAA78593 XM_011245833 XP_011244135 NM_008310 NP_032336
|
| Function |
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. {ECO:0000269|PubMed:1328180}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:1328180}; Multi-pass membrane protein {ECO:0000269|PubMed:1328180}.
|
| Tissue Specificity |
Detected in hippocampus. {ECO:0000269|PubMed:1328180}.
|
| Top Pathways |
cAMP signaling pathway, Neuroactive ligand-receptor interaction
|