Chil3

Gene Symbol	Chil3
Entrez Gene	12655
Alt Symbol	AI505981, Chi3l3, ECF-L, Ym1
Species	Mouse
Gene Type	protein-coding
Description	chitinase-like 3
Other Description	beta-N-acetylhexosaminidase Ym1|chitinase 3-like 3|chitinase-3-like protein 3|chitinase-like protein 3|eosinophil chemotactic cytokine|eosinophil chemotactic factor-L|secreted protein Ym1
Swissprots	P70201 Q3UV87 Q3U462 Q61201 O35744
Accessions	AAN04032 O35744 AK137503 BAE23385 AK154420 BAE32572 BC061154 AAH61154 BY117835 D87757 BAA13458 M94584 AAB62394 U56900 AAB01230 NM_009892 NP_034022
Function	Lectin that binds saccharides with a free amino group, such as glucosamine or galactosamine. Binding to oligomeric saccharides is much stronger than binding to mono- or disaccharides. Also binds chitin and heparin. Has weak hexosaminidase activity but no chitinase activity. Has chemotactic activity for T-lymphocytes, bone marrow cells and eosinophils. May play a role in inflammation and allergy. {ECO:0000269|PubMed:10625674, ECO:0000269|PubMed:11297523, ECO:0000269|PubMed:11733538}.
Subcellular Location	Secreted. Rough endoplasmic reticulum lumen. Nucleus envelope. Cytoplasm. Cytoplasmic granule. Note=Predominantly localizes to the lumen of rough endoplasmic reticulum (rER) and nuclear envelope in alveolar macrophages. Localizes to the dilated lumen of rER in immature neutrophils in spleen and in cytoplasmic granules in peritoneal neutrophils. Detected in needle-shaped crystals present in the cytoplasm of bone marrow macrophages.
Tissue Specificity	Expressed in peritoneal cavity macrophages and in peritoneal and bone marrow-derived neutrophils. Abundantly expressed in bone marrow, with moderate levels detected in gastric antrum, spleen and in alveolar macrophages in lung. Not detected in brain, heart, liver, kidney, stomach, intestine, skeletal muscle, ovary, testis, thymus and lymph nodes (at protein level). Detected at low levels in bone marrow, spleen, thymus and lung. Barely detectable in intestine, kidney and coecum. {ECO:0000269|PubMed:10625674, ECO:0000269|PubMed:11297523, ECO:0000269|PubMed:11733538, ECO:0000269|PubMed:12101265, ECO:0000269|PubMed:15148607, ECO:0000269|PubMed:9828134}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Recombinant Mouse Chitinase 3-like 3/ECF-L, CF - 2446-CH-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Met1-Tyr398, with a C-terminal 6-His tag

Mouse Chitinase-like 3 (His Tag) protein - orb232649 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Species Mouse

Recombinant Mouse Chil3, His-tagged - Chil3-627M from Creative Biomart Category Protein Source NSO Cells Species Mouse

Mouse Chitinase-like 3 / Chi3l3 Protein (His Tag) - 51165-M08H-100 from Sino Biological Category Protein Source Human Cells Species Mouse

Recombinant Mouse Chitinase-3-like protein 3(Chi3l3) - CSB-YP518578MO CSB-EP518578MO CSB-BP518578MO CSB-MP518578MO from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Mouse

Recombinant Mouse YM1/Chitinase 3-like 3 Protein, CF - 2446-CH from R&D Systems Category Protein Prices $329.00 Sizes 50 µg Source Mouse myeloma cell line, NS0-derived Met1-Tyr398, with a C-terminal 6-His tag Species Mouse

Recombinant Mouse Chitinase-like 3 / Chi3l3 Protein (His tag) - PKSM040334 from Elabscience Category Protein Source Human Cells Species Mouse

Recombinant Mouse CHI3L3 Protein - CHI3L3-3393M from Creative Biomart Category Protein Source Mammalian Cells Species Mouse

Chitinase-3-like protein 3 (Chi3l3), Recombinant Protein - MBS1021545 from MyBioSource Category Protein Prices $1,145.00, $1,145.00, $1,375.00, $1,375.00, $1,825.00, $1,825.00, $2,290.00, $2,290.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Mouse

Chitinase-like 3 / Chi3l3, Recombinant Protein - MBS2546637 from MyBioSource Category Protein Prices $475.00, $775.00 Sizes 50 µg, 100 µg Source Human Cells

Recombinant Mouse YM1/Chitinase 3-like 3 Protein, CF - 2446-CH from Novus Biologicals Category Protein Prices $329.00 Sizes 50 µg

Recombinant Mouse Chitinase-Like Protein 3 ,YM1,ECF-L,CHI3L3 (C-6His) - AP76471 from Signalway Antibody Category Protein Prices $259.00, $479.00, $1,699.00, $2,369.00 Sizes 10 µg, 50 µg, 500 µg, 1 mg Source Human Cells Species Mouse

Mouse YM1 protein - orb55961 from Biorbyt Category Protein Species Mouse

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