| Gene Symbol |
MTNR1B
|
| Entrez Gene |
4544
|
| Alt Symbol |
FGQTL2, MEL-1B-R, MT2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
melatonin receptor 1B
|
| Other Description |
mel1b receptor|melatonin receptor MEL1B|melatonin receptor type 1B
|
| Swissprots |
P49286
|
| Accessions |
BAA92315 EAW66891 P49286 AF467654 AAL75503 AY114100 AAM78367 AY521019 AAS00461 BC069163 AAH69163 U25341 AAC50612 XM_011542839 XP_011541141 NM_005959 NP_005950
|
| Function |
High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Expressed in retina and less in brain and hippocampus.
|
| Top Pathways |
Circadian entrainment, Neuroactive ligand-receptor interaction
|
![Western Blot: Melatonin Receptor 1B Overexpression Lysate (Adult Normal) [NBP2-04305] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Melatonin Receptor 1B.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8735_Melatonin%2520Receptor%25201B%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-04305-img0001.jpg)