DGKG

Gene Symbol DGKG
Entrez Gene 1608
Alt Symbol DAGK3, DGK-GAMMA
Species Human
Gene Type protein-coding
Description diacylglycerol kinase, gamma 90kDa
Other Description DAG kinase gamma|diacylglycerol kinase gamma|diacylglyerol kinase gamma|diglyceride kinase gamma
Swissprots Q2M1H4 P49619 Q5FWG1 B2RAH4
Accessions AAC04686 P49619 AB209033 BAD92270 AK304440 BAH14187 AK309682 AK314192 BAG36871 AY737485 AAW63408 BC089411 AAH89411 BC112363 AAI12364 BM669549 D26135 BAA05132 NM_001080744 NP_001074213 NM_001080745 NP_001074214 NM_001346 NP_001337
Function Reverses the normal flow of glycerolipid biosynthesis by phosphorylating diacylglycerol back to phosphatidic acid.
Subcellular Location Cytoplasm. Membrane. Note=Can be loosely bound to the membranes.
Tissue Specificity Predominantly expressed in retina and in a much lesser extent in the brain. Other tissues contain extremely low levels of DGK-gamma.
Top Pathways Choline metabolism in cancer, Glycerolipid metabolism, Glycerophospholipid metabolism, Phosphatidylinositol signaling system