Gene Symbol | DGKG |
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Entrez Gene | 1608 |
Alt Symbol | DAGK3, DGK-GAMMA |
Species | Human |
Gene Type | protein-coding |
Description | diacylglycerol kinase, gamma 90kDa |
Other Description | DAG kinase gamma|diacylglycerol kinase gamma|diacylglyerol kinase gamma|diglyceride kinase gamma |
Swissprots | Q2M1H4 P49619 Q5FWG1 B2RAH4 |
Accessions | AAC04686 P49619 AB209033 BAD92270 AK304440 BAH14187 AK309682 AK314192 BAG36871 AY737485 AAW63408 BC089411 AAH89411 BC112363 AAI12364 BM669549 D26135 BAA05132 NM_001080744 NP_001074213 NM_001080745 NP_001074214 NM_001346 NP_001337 |
Function | Reverses the normal flow of glycerolipid biosynthesis by phosphorylating diacylglycerol back to phosphatidic acid. |
Subcellular Location | Cytoplasm. Membrane. Note=Can be loosely bound to the membranes. |
Tissue Specificity | Predominantly expressed in retina and in a much lesser extent in the brain. Other tissues contain extremely low levels of DGK-gamma. |
Top Pathways | Choline metabolism in cancer, Glycerolipid metabolism, Glycerophospholipid metabolism, Phosphatidylinositol signaling system |
DGK-γ CRISPR/Cas9 KO Plasmid (h) - sc-409603 from Santa Cruz Biotechnology
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DGK-γ HDR Plasmid (h) - sc-409603-HDR from Santa Cruz Biotechnology
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DGK-γ Double Nickase Plasmid (h) - sc-409603-NIC from Santa Cruz Biotechnology
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DGK-γ Double Nickase Plasmid (h2) - sc-409603-NIC-2 from Santa Cruz Biotechnology
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DGK-γ CRISPR Activation Plasmid (h) - sc-409603-ACT from Santa Cruz Biotechnology
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DGK-γ CRISPR Activation Plasmid (h2) - sc-409603-ACT-2 from Santa Cruz Biotechnology
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DGK-γ Lentiviral Activation Particles (h) - sc-409603-LAC from Santa Cruz Biotechnology
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DGK-γ Lentiviral Activation Particles (h2) - sc-409603-LAC-2 from Santa Cruz Biotechnology
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DGK-γ siRNA (h) - sc-60527 from Santa Cruz Biotechnology
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DGK-g shRNA Plasmid (h) - sc-60527-SH from Santa Cruz Biotechnology
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DGK-g shRNA (h) Lentiviral Particles - sc-60527-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU077261 from Sigma-Aldrich
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MISSION® siRNA - SIHK0580 from Sigma-Aldrich
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MISSION® siRNA - SIHK0583 from Sigma-Aldrich
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MISSION® siRNA - SIHK0582 from Sigma-Aldrich
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MISSION® siRNA - SIHK0585 from Sigma-Aldrich
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MISSION® siRNA - SIHK0581 from Sigma-Aldrich
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MISSION® siRNA - SIHK0584 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7182 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7182 from Sigma-Aldrich
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DGKG siRNA (Human) - CRH1131 from Cohesion Biosciences
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DGK-gamma RNAi - H00001608-R03 from Novus Biologicals
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DGKG - MBS8217730 from MyBioSource
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shRNA set against Human DGKG (NM_001346.2) - SHH277489 from Creative biogene
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shRNA set against Human DGKG(NM_001080744.1) - SHH002945 from Creative biogene
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