| Gene Symbol |
Sec61a2
|
| Entrez Gene |
57743
|
| Alt Symbol |
-
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
Sec61, alpha subunit 2 (S. cerevisiae)
|
| Other Description |
Sec61 alpha|protein transport protein Sec61 subunit alpha|protein transport protein Sec61 subunit alpha isoform 2|sec61 alpha-2
|
| Swissprots |
Q9JLR1
|
| Accessions |
EDL07972 EDL07973 Q9JLR1 AF145254 AAF66696 AF222748 AAG44253 AK017615 BAB30840 AK077701 BAC36967 AK136447 AK160602 AK161316 BAE36319 BC005458 AAH05458 XM_006497515 XP_006497578 XM_006497516 XP_006497579 XM_006497517 XP_006497580 XR_373943 NM_021305 NP_067280
|
| Function |
Appears to play a crucial role in the insertion of secretory and membrane polypeptides into the ER. It is required for assembly of membrane and secretory proteins. Found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
| Top Pathways |
Protein export, Phagosome, Protein processing in endoplasmic reticulum
|