Gene Symbol |
MSRA
|
Entrez Gene |
4482
|
Alt Symbol |
PMSR
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
methionine sulfoxide reductase A
|
Other Description |
cytosolic methionine-S-sulfoxide reductase|mitochondrial peptide methionine sulfoxide reductase|peptide Met(O) reductase|peptide met (O) reductase|peptide-methionine (S)-S-oxide reductase
|
Swissprots |
E9PAS8 Q52TC4 Q9UJ68 Q66MI7 Q549N4
|
Accessions |
AAY17429 AAY17430 AAY17431 CBA34903 EAW65584 EAW65585 Q9UJ68 AF086925 AAP97154 AF183420 AAG09689 AI261219 AJ242973 CAB59628 AK123132 AK293488 BAH11521 AK299948 BAH13180 AY690665 AAU11088 AY958429 AAY17426 AY958430 AAY17427 AY958431 AAY17428 BC047552 BC054033 AAH54033 CK819753 XM_011543822 XP_011542124 XM_011543823 XP_011542125 NM_001135670 NP_001129142 NM_001135671 NP_001129143 NM_001199729 NP_001186658 NM_012331 NP_036463
|
Function |
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
|
Subcellular Location |
Isoform 3: Cytoplasm. Nucleus.
|
Tissue Specificity |
Ubiquitous. Highest expression in adult kidney and cerebellum, followed by liver, heart ventricles, bone marrow and hippocampus.
|