Gene Symbol | MSRA |
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Entrez Gene | 4482 |
Alt Symbol | PMSR |
Species | Human |
Gene Type | protein-coding |
Description | methionine sulfoxide reductase A |
Other Description | cytosolic methionine-S-sulfoxide reductase|mitochondrial peptide methionine sulfoxide reductase|peptide Met(O) reductase|peptide met (O) reductase|peptide-methionine (S)-S-oxide reductase |
Swissprots | E9PAS8 Q52TC4 Q9UJ68 Q66MI7 Q549N4 |
Accessions | AAY17429 AAY17430 AAY17431 CBA34903 EAW65584 EAW65585 Q9UJ68 AF086925 AAP97154 AF183420 AAG09689 AI261219 AJ242973 CAB59628 AK123132 AK293488 BAH11521 AK299948 BAH13180 AY690665 AAU11088 AY958429 AAY17426 AY958430 AAY17427 AY958431 AAY17428 BC047552 BC054033 AAH54033 CK819753 XM_011543822 XP_011542124 XM_011543823 XP_011542125 NM_001135670 NP_001129142 NM_001135671 NP_001129143 NM_001199729 NP_001186658 NM_012331 NP_036463 |
Function | Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. |
Subcellular Location | Isoform 3: Cytoplasm. Nucleus. |
Tissue Specificity | Ubiquitous. Highest expression in adult kidney and cerebellum, followed by liver, heart ventricles, bone marrow and hippocampus. |
MsrA CRISPR/Cas9 KO Plasmid (h) - sc-404424 from Santa Cruz Biotechnology
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MsrA HDR Plasmid (h) - sc-404424-HDR from Santa Cruz Biotechnology
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MsrA Double Nickase Plasmid (h) - sc-404424-NIC from Santa Cruz Biotechnology
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MsrA Double Nickase Plasmid (h2) - sc-404424-NIC-2 from Santa Cruz Biotechnology
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MsrA CRISPR Activation Plasmid (h) - sc-404424-ACT from Santa Cruz Biotechnology
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MsrA CRISPR Activation Plasmid (h2) - sc-404424-ACT-2 from Santa Cruz Biotechnology
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MsrA Lentiviral Activation Particles (h) - sc-404424-LAC from Santa Cruz Biotechnology
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MsrA Lentiviral Activation Particles (h2) - sc-404424-LAC-2 from Santa Cruz Biotechnology
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MsrA siRNA (h) - sc-72126 from Santa Cruz Biotechnology
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MsrA shRNA Plasmid (h) - sc-72126-SH from Santa Cruz Biotechnology
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MsrA shRNA (h) Lentiviral Particles - sc-72126-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU043851 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14658 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14658 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05151 from Sigma-Aldrich
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MSRA siRNA (Human) - CRH2976 from Cohesion Biosciences
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shRNA set against Human MSRA (NM_012331.3) - SHH345808 from Creative biogene
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Human MSRA siRNA - orb263478 from Biorbyt
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MSRA shRNA Plasmid (Human) - CHH2976 from Cohesion Biosciences
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MSRA miRNA 3'UTR clone - MiUTR3H-03995 from Creative biogene
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MSRA miRNA 3'UTR clone - MiUTR3H-03996 from Creative biogene
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MSRA miRNA 3'UTR clone - MiUTR3H-03997 from Creative biogene
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