Gene Symbol | HIST1H1C |
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Entrez Gene | 3006 |
Alt Symbol | H1.2, H1C, H1F2, H1s-1 |
Species | Human |
Gene Type | protein-coding |
Description | histone cluster 1, H1c |
Other Description | H1 histone family, member 2|histone 1, H1c|histone H1.2|histone H1c|histone H1d|histone H1s-1 |
Swissprots | A8K4I2 P16403 |
Accessions | AAN06700 CAA40408 EAW55515 P16403 AB451259 BAG70073 AB451385 BAG70199 AK290947 BAF83636 BC002649 D28457 BAA05823 EU446960 ABZ92489 EU832089 ACE87439 EU832181 ACE86751 NM_005319 NP_005310 |
Function | Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus. Chromosome. Note=Mainly localizes in euchromatin. Distribution goes in parallel with DNA concentration. |
Histone cluster 1 H1C CRISPR/Cas9 KO Plasmid (h) - sc-407712 from Santa Cruz Biotechnology
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Histone cluster 1 H1C HDR Plasmid (h) - sc-407712-HDR from Santa Cruz Biotechnology
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Histone cluster 1 H1C Double Nickase Plasmid (h) - sc-407712-NIC from Santa Cruz Biotechnology
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Histone cluster 1 H1C Double Nickase Plasmid (h2) - sc-407712-NIC-2 from Santa Cruz Biotechnology
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Histone cluster 1 H1C CRISPR Activation Plasmid (h) - sc-407712-ACT from Santa Cruz Biotechnology
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Histone cluster 1 H1C CRISPR Activation Plasmid (h2) - sc-407712-ACT-2 from Santa Cruz Biotechnology
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Histone cluster 1 H1C Lentiviral Activation Particles (h) - sc-407712-LAC from Santa Cruz Biotechnology
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Histone cluster 1 H1C Lentiviral Activation Particles (h2) - sc-407712-LAC-2 from Santa Cruz Biotechnology
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Histone cluster 1 H1C siRNA (h) - sc-37970 from Santa Cruz Biotechnology
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Histone cluster 1 H1C shRNA Plasmid (h) - sc-37970-SH from Santa Cruz Biotechnology
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Histone cluster 1 H1C shRNA (h) Lentiviral Particles - sc-37970-V from Santa Cruz Biotechnology
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Histone H1.2 RNAi - H00003006-R01 from Novus Biologicals
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MISSION® esiRNA - EHU014531 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10052 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10052 from Sigma-Aldrich
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HIST1H1C siRNA (Human) - CRH2041 from Cohesion Biosciences
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HIST1H1C - MBS8234521 from MyBioSource
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shRNA set against Human HIST1H1C (NM_005319.3) - SHH312381 from Creative biogene
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Human HIST1H1C siRNA - orb262543 from Biorbyt
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HIST1H1C shRNA Plasmid (Human) - CHH2041 from Cohesion Biosciences
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HIST1H1C miRNA 3'UTR clone - MiUTR1H-04515 from Creative biogene
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