GGA1

Gene Symbol GGA1
Entrez Gene 26088
Alt Symbol -
Species Human
Gene Type protein-coding
Description golgi-associated, gamma adaptin ear containing, ARF binding protein 1
Other Description ADP-ribosylation factor binding protein 1|ADP-ribosylation factor-binding protein GGA1|gamma-adaptin related protein 1|gamma-adaptin-related protein 1|golgi associated, gamma adaptin ear containing, ARF binding protein 1|golgi-localized, gamma ear-containing, ARF-binding protein 1
Swissprots A8K3D3 B0QYR7 Q9UG00 Q9UGW1 Q6IC75 Q9UJY5 Q5R3N1 Q5TG07 Q9BW94 Q9UGW0 Q86YA9 Q8NCS6
Accessions CAF86574 EAW60168 EAW60169 EAW60170 Q9UJY5 AF190862 AAF05707 AF218584 AAF42847 AF233521 AAF35393 AK075256 BAC11501 AK092417 AK095427 BAG53054 AK097270 AK122898 BAG53788 AK225157 AK290548 BAF83237 AL110219 CAB53679 BC000538 AAH00538 BC010917 AAH10917 BC029388 AAH29388 BC044629 AAH44629 CR456493 CAG30379 CU013090 CAK54521 CU013378 CAK54820 DA455573 DQ593821 XM_005261517 XP_005261574 XM_005261518 XP_005261575 XM_005261520 XP_005261577 XM_005261522 XP_005261579 XM_006724229 XP_006724292 XM_011530122 XP_011528424 XM_011530123 XP_011528425 XM_011530124 XP_011528426 XM_011530125 XP_011528427 NM_001001560 NP_001001560 NM_001172687 NP_001166158 NM_001172688 NP_001166159 NM_013365 NP_037497 NM_001001561
Function Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif. {ECO:0000269|PubMed:11301005}.
Subcellular Location Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein.
Tissue Specificity Ubiquitously expressed.
Top Pathways Lysosome

GGA1 (A-1) - sc-390837 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GGA1 (A-1): sc-390837. Western blot analysis of GGA1 expression in non-transfected: sc-117752 (A) and mouse GGA1 transfected: sc-120473 (B) 293T whole cell lysates.

GGA1 (D-6) - sc-271927 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GGA1 (D-6): sc-271927. Western blot analysis of GGA1 expression in non-transfected 293T: sc-117752 (A), human GGA1 transfected 293T: sc-128702 (B), HEK293 (C) and Jurkat (D) whole cell lysates.

GGA1 (D-8) - sc-390420 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GGA1 (D-8): sc-390420. Western blot analysis of GGA1 expression in non-transfected: sc-117752 (A) and human GGA1 transfected: sc-128702 (B) whole cell lysates.

GGA1 (G-17) - sc-23262 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GGA1 (G-17): sc-23262. Western blot analysis of GGA1 expression in non-transfected: sc-117752 (A) and human GGA1 transfected: sc-128702 (B) 293T whole cell lysates.

GGA1 (H-215) - sc-30102 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
GGA1 (H-215): sc-30102. Western blot analysis of GGA1 expression in non-transfected 293T: sc-117752 (A), mouse GGA1 transfected 293T: sc-120473 (B) and HeLa (C) whole cell lysates.

GGA1 (N-20) - sc-23261 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GGA1 (N-20): sc-23261. Western blot analysis of GGA1 expression in HeLa (A), Jurkat (B) and SK-N-SH (C) whole cell lysates.

Anti-GGA1 antibody - ab153799 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-GGA1 antibody (ab153799) at 1/1000 dilutionLane 1 : NT2D1 whole cell lysateLane 2 : PC-3 whole cell lysateLane 3 : U87-MG whole cell lysateLane 4 : SK-N-SH whole cell lysateLysates/proteins at 30 µg per lane.

Anti-GGA1 antibody - ab10551 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-GGA1 antibody (ab10551) at 1/1350 dilution + Lysate of HEK293 cells overexpressing YFP-GGA1 fusion protein at 35 µg/mlSecondaryGoat-anti Rabbit IgG at 10000 Performed under reducing conditions.

Anti-GGA1 antibody - ab38454 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-GGA1 antibody (ab38454) at 1/100 dilutionLane 1 : Mouse kidney tissue lysateLane 2 : Jurkat cell lysate

Anti-GGA1 antibody - ab57247 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
GGA1 antibody (ab57247) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human stomach.

Anti-GGA1 antibody - ab128380 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-GGA1 antibody (ab128380) at 1 µg/ml + Jurkat cell lysate at 10 µg

Anti-GGA1 antibody [EPR3014(2)] - ab170956 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3014(2)
Western blot analysis on Immunoprecipitation pellet from Jurkat cells showing GGA1, using ab170956 at 1/10 dilution for IP.

Anti-GGA1 Antibody (aa170-220) - LS-C94170 from LifeSpan Bioscience

Prices $325.00
Sizes 500 µg
Host Rabbit
Clonality Polyclonal

Anti-GGA1 Antibody (aa1-30, AP) - LS-C235623 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GGA1 Antibody (aa1-30, Biotin) - LS-C235625 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GGA1 Antibody (N-Terminus) - LS-C210112 from LifeSpan Bioscience

Prices $295.00
Sizes 250 µl
Host Rabbit
Clonality Polyclonal

Anti-GGA1 Antibody (aa1-30, FITC) - LS-C235626 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GGA1 Antibody (aa1-30, PE) - LS-C235630 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GGA1 Antibody (aa1-30, APC) - LS-C235624 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GGA1 Antibody (aa1-30, Azide-free, HRP) - LS-C249057 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GGA1 Antibody - LS-C307681 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-GGA1 Antibody (aa86-135) - LS-C151565 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
GGA1 antibody Western Blot of Jurkat.

Anti-GGA1 Antibody - LS-C310475 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GGA1 Antibody (aa336-352) - LS-C19101 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-GGA1 Antibody - Western Blot. Western blot of Affinity Purified anti-GGA1 antibody shows detection of bands at ~100 kD corresponding to YFP-GGA1 fusion present in a lysate of HEK293 cells over- expressing the recombinant protein (arrowhead). Approximately 35 ug of lysate was separated on a 4-20% gel by SDS-PAGE and transferred onto nitrocellulose. After blocking the membrane was probed with the primary antibody diluted to 1:1350. Reaction occurred overnight at 4? followed by washes and reaction with a 1:10000 dilution of IRDye800 conjugated Rb-a-Goat IgG [H&L] MXHu ( for 45 min at room temperature. IRDye800 fluorescence image was captured using the Odyssey Infrared Imaging System developed by LI-COR. IRDye is a trademark of LI-COR, Inc. Other detection systems will yield similar results.

Anti-GGA1 Antibody (aa1-30) - LS-C321616 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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